version: 3.0

bZIP Family

Description

Jakoby et al. 2002: In plants, basic region/leucine zipper motif (bZIP) transcription factors regulate processes including pathogen defence, light and stress signalling, seed maturation and flower development.

Members of this family
SHOULD possess bZIP_1 bZIP_2 bZIP_Maf domains
SHOULD NOT possess HLH domain

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for this family. The data reported by Jakoby et al. 2002 for A. thaliana were taken as gold standard.

The gold standard reported 74 members for this family, 68 of which are present in ArabTFDB, giving a PPV of 0.97. Six additional members not present in ArabTFDB might be false negatives, giving a Sensitivity of 0.92.

This family is also present in:

References

General references

Corrêa, LG; Riaño-Pachón, DM; Schrago, CG; dos Santos, RV; Mueller-Roeber, B; Vincentz, M. 2008. The role of bZIP transcription factors in green plant evolution: adaptive features emerging from four founder genes. PLoS ONE 3(8):e2944 PUBMEDID:18698409
Foster, R; Izawa, T; Chua, NH. 1994. Plant bZIP proteins gather at ACGT elements. FASEB J. 8(2):192-200 PUBMEDID:8119490
Hurst, HC. 1995. Transcription factors 1: bZIP proteins. Protein Profile 2(2):101-68 PUBMEDID:7780801
Landschulz, WH; Johnson, PF; McKnight, SL. 1988. The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. Science 240(4860):1759-64 PUBMEDID:3289117
Vinson, C; Acharya, A; Taparowsky, EJ. 2006. Deciphering B-ZIP transcription factor interactions in vitro and in vivo. Biochim. Biophys. Acta 1759(1-2):4-12 PUBMEDID:16580748