Plant Transcription factor database - Universität Potsdam
version: 3.0

Oryza sativa subsp. japonica AP2-EREBP Family

Description

Riechmann & Meyerowitz. 1998: AP2 (APETALA2) and EREBPs (ethylene-responsive element binding proteins) are the prototypic members of a family of transcription factors unique to plants, whose distinguishing characteristic is that they contain the so-called AP2 DNA-binding domain. AP2/ REBP genes form a large multigene family, and they play a variety of roles throughout the plant life cycle: from being key regulators of several developmental processes, like floral organ identity determination or control of leaf epidermal cell identity, to forming part of the mechanisms used by plants to respond to various types of biotic and environmental stress.

Shigyo et al. 2006: AP2/EREBP genes are divided into two subfamilies: AP2 genes with two AP2 domains and EREBP genes with a single AP2/ERF (Ethylene Responsive Element Binding Factor) domain. Expressions of AP2-like genes, including AP2, in Arabidopsis thaliana are regulated by the microRNA miR172. We found that the target site of miR172 is significantly conserved in gymnosperm AP2 homologs, suggesting that regulatory mechanisms of gene expression using microRNA have been conserved over the three hundred million years since the divergence of gymnosperm and flowering plant lineages.

Members of this family
  SHOULD possess AP2 domain

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for this family. The data reported by Feng et al. 2005 for A. thaliana were taken as gold standard.

The gold standard reported 147 members for this family, 146 of which are present in ArabTFDB, giving a PPV of 1.00. One additional member not present in ArabTFDB might be a false negative, giving a Sensitivity of 0.99.

This family is also present in:

References

There are 196 gene models in this family



Gene modelDescriptionDomains
LOC_Os01g04020.1 AP2 domain containing protein, expressed AP2
LOC_Os01g04020.2 AP2 domain containing protein, expressed AP2
LOC_Os01g04750.1 B3 DNA binding domain containing protein, expressed AP2 B3
LOC_Os01g04800.1 B3 DNA binding domain containing protein, expressed AP2 B3
LOC_Os01g07120.1 AP2 domain containing protein, expressed AP2
LOC_Os01g07120.2 AP2 domain containing protein, expressed AP2
LOC_Os01g10370.1 AP2 domain containing protein, expressed AP2
LOC_Os01g12440.1 AP2 domain containing protein, expressed AP2
LOC_Os01g21120.1 AP2 domain containing protein, expressed AP2
LOC_Os01g46870.1 AP2 domain containing protein, expressed AP2
LOC_Os01g49830.1 B3 DNA binding domain containing protein, expressed AP2 B3
LOC_Os01g54890.1 ethylene-responsive transcription factor 2, putative, expressed AP2
LOC_Os01g58420.1 AP2 domain containing protein, expressed AP2
LOC_Os01g59780.1 AP2 domain containing protein, expressed AP2
LOC_Os01g64790.1 AP2 domain containing protein, expressed AP2
LOC_Os01g66270.1 AP2 domain containing protein, expressed AP2
LOC_Os01g67410.1 AP2/EREBP transcription factor BABY BOOM, putative, expressed AP2
LOC_Os01g73770.1 dehydration-responsive element-binding protein, putative, expressed AP2
LOC_Os02g06330.1 AP2 domain containing protein, expressed AP2
LOC_Os02g09650.1 AP2 domain containing protein, expressed AP2
LOC_Os02g10760.1 AP2 domain containing protein, expressed AP2
LOC_Os02g13710.1 ethylene-responsive transcription factor TINY, putative, expressed AP2
LOC_Os02g29550.1 AP2 domain containing protein, expressed AP2
LOC_Os02g29550.2 AP2 domain containing protein, expressed AP2
LOC_Os02g29550.3 AP2 domain containing protein, expressed AP2
LOC_Os02g32040.1 AP2 domain containing protein AP2
LOC_Os02g32140.1 AP2 domain containing protein, expressed AP2
LOC_Os02g34260.1 AP2 domain containing protein AP2
LOC_Os02g34270.1 AP2 domain containing protein, expressed AP2
LOC_Os02g35240.1 dehydration-responsive element-binding protein, putative AP2
LOC_Os02g38090.1 AP2 domain containing protein AP2
LOC_Os02g40070.1 AP2-like ethylene-responsive transcription factor PLETHORA 2, putative, expressed AP2
LOC_Os02g42585.1 AP2 domain containing protein, expressed AP2
LOC_Os02g43790.1 ethylene-responsive transcription factor, putative, expressed AP2
LOC_Os02g43820.1 AP2 domain containing protein, expressed AP2
LOC_Os02g43940.1 AP2 domain containing protein, expressed AP2
LOC_Os02g43970.1 AP2 domain containing protein, expressed AP2
LOC_Os02g45420.1 AP2 domain containing protein, expressed AP2
LOC_Os02g45450.1 dehydration-responsive element-binding protein, putative, expressed AP2
LOC_Os02g51300.1 AP2 domain containing protein, expressed AP2
LOC_Os02g51670.1 ethylene-responsive transcription factor, putative, expressed AP2
LOC_Os02g52670.1 AP2 domain containing protein, expressed AP2
LOC_Os02g54050.1 ethylene-responsive transcription factor, putative, expressed AP2
LOC_Os02g54160.1 AP2 domain containing protein, expressed AP2
LOC_Os02g54160.2 AP2 domain containing protein, expressed AP2
LOC_Os02g55380.1 AP2 domain containing protein, expressed AP2
LOC_Os03g05590.1 AP2 domain containing protein, expressed AP2
LOC_Os03g06920.1 DRD1, putative, expressed AP2 Helicase_C SNF2_N
LOC_Os03g07830.1 AP2 domain containing protein AP2
LOC_Os03g07940.1 AP2 domain containing protein, expressed AP2
LOC_Os03g08460.1 AP2 domain containing protein, expressed AP2
LOC_Os03g08470.1 AP2 domain containing protein, expressed AP2
LOC_Os03g08470.2 AP2 domain containing protein, expressed AP2
LOC_Os03g08470.3 AP2 domain containing protein, expressed AP2
LOC_Os03g08490.1 AP2 domain containing protein, expressed AP2
LOC_Os03g08500.1 AP2 domain containing protein, expressed AP2
LOC_Os03g08500.2 AP2 domain containing protein, expressed AP2
LOC_Os03g09170.1 ethylene-responsive transcription factor, putative, expressed AP2
LOC_Os03g12950.1 AP2-like ethylene-responsive transcription factor AINTEGUMENTA, putative, expressed AP2
LOC_Os03g15660.1 AP2 domain containing protein, expressed AP2
LOC_Os03g19900.1 AP2 domain containing protein, expressed AP2
LOC_Os03g22170.1 AP2 domain containing protein, expressed AP2
LOC_Os03g56050.1 AP2-like ethylene-responsive transcription factor AINTEGUMENTA, putative, expressed AP2
LOC_Os03g60120.1 AP2 domain containing protein, expressed AP2
LOC_Os03g60430.1 AP2 domain containing protein, expressed AP2
LOC_Os03g60430.2 AP2 domain containing protein, expressed AP2
LOC_Os03g64260.1 AP2 domain containing protein, expressed AP2
LOC_Os04g18650.1 AP2 domain containing protein AP2
LOC_Os04g32620.1 ethylene-responsive transcription factor ERF114, putative, expressed AP2
LOC_Os04g32790.1 AP2 domain containing protein, expressed AP2
LOC_Os04g34970.1 AP2 domain containing protein, expressed AP2
LOC_Os04g36640.1 dehydration-responsive element-binding protein, putative AP2
LOC_Os04g42570.1 AP2/EREBP transcription factor BABY BOOM, putative, expressed AP2
LOC_Os04g44670.1 AP2 domain containing protein, expressed AP2
LOC_Os04g46220.1 ethylene-responsive transcription factor, putative, expressed AP2
LOC_Os04g46240.1 AP2 domain containing protein, expressed AP2
LOC_Os04g46250.1 AP2 domain containing protein, expressed AP2
LOC_Os04g46400.1 AP2 domain containing protein, expressed AP2
LOC_Os04g46410.1 AP2 domain containing protein, expressed AP2
LOC_Os04g46440.1 AP2 domain containing protein, expressed AP2
LOC_Os04g48350.1 dehydration-responsive element-binding protein, putative, expressed AP2
LOC_Os04g52090.1 AP2 domain containing protein, expressed AP2
LOC_Os04g55520.1 AP2 domain containing protein, expressed AP2
LOC_Os04g55560.2 AP2 domain containing protein, expressed AP2
LOC_Os04g55560.3 AP2 domain containing protein, expressed AP2
LOC_Os04g55970.1 AP2-like ethylene-responsive transcription factor AINTEGUMENTA, putative, expressed AP2
LOC_Os04g55970.2 AP2-like ethylene-responsive transcription factor AINTEGUMENTA, putative, expressed AP2
LOC_Os04g56150.1 AP2 domain containing protein AP2
LOC_Os04g57340.1 AP2 domain containing protein, expressed AP2
LOC_Os05g03040.1 AP2 domain containing protein, expressed AP2
LOC_Os05g03040.2 AP2 domain containing protein, expressed AP2
LOC_Os05g03040.3 AP2 domain containing protein, expressed AP2
LOC_Os05g25260.1 AP2 domain containing protein, expressed AP2
LOC_Os05g27930.1 AP2 domain containing protein, expressed AP2
LOC_Os05g27930.2 AP2 domain containing protein, expressed AP2
LOC_Os05g27930.3 AP2 domain containing protein, expressed AP2
LOC_Os05g27930.4 AP2 domain containing protein, expressed AP2
LOC_Os05g28350.1 AP2 domain containing protein, expressed AP2
LOC_Os05g29810.1 AP2 domain containing protein, expressed AP2
LOC_Os05g32270.1 AP2 domain containing protein, expressed AP2
LOC_Os05g34730.1 ethylene-responsive transcription factor ERF020, putative, expressed AP2
LOC_Os05g36100.1 AP2 domain containing protein, expressed AP2
LOC_Os05g37640.1 hypothetical protein AP2
LOC_Os05g39590.1 AP2 domain containing protein, expressed AP2
LOC_Os05g39590.2 AP2 domain containing protein, expressed AP2
LOC_Os05g39590.3 AP2 domain containing protein, expressed AP2
LOC_Os05g41760.1 AP2 domain containing protein, expressed AP2
LOC_Os05g41780.1 AP2 domain containing protein, expressed AP2
LOC_Os05g45954.1 AP2 domain containing protein, expressed AP2
LOC_Os05g47650.1 B3 DNA binding domain containing protein, expressed AP2 B3
LOC_Os05g49010.1 AP2 domain containing protein, expressed AP2
LOC_Os05g49700.1 AP2 domain containing protein, expressed AP2
LOC_Os06g03670.1 dehydration-responsive element-binding protein, putative, expressed AP2
LOC_Os06g05340.1 AP2 domain containing protein AP2
LOC_Os06g06540.1 AP2 domain containing protein AP2
LOC_Os06g06970.1 AP2 domain containing protein, expressed AP2
LOC_Os06g07030.1 AP2 domain containing protein, expressed AP2
LOC_Os06g08340.1 AP2 domain containing protein AP2
LOC_Os06g09390.1 AP2 domain containing protein, expressed AP2
LOC_Os06g09390.2 AP2 domain containing protein, expressed AP2
LOC_Os06g09717.1 ethylene-responsive transcription factor, putative AP2
LOC_Os06g09760.1 AP2 domain containing protein AP2
LOC_Os06g09790.1 ethylene-responsive transcription factor, putative, expressed AP2
LOC_Os06g09810.1 ethylene-responsive transcription factor, putative AP2
LOC_Os06g10780.1 AP2 domain containing protein, expressed AP2
LOC_Os06g11860.1 ethylene-responsive transcription factor, putative, expressed AP2
LOC_Os06g11940.1 dehydration-responsive element binding protein, putative, expressed AP2
LOC_Os06g36000.1 AP2 domain containing protein, expressed AP2
LOC_Os06g40150.1 AP2 domain containing protein, expressed AP2
LOC_Os06g42990.1 AP2 domain containing protein AP2
LOC_Os06g43220.1 AP2 domain containing protein, expressed AP2
LOC_Os06g44750.1 AP2 domain containing protein, expressed AP2
LOC_Os06g47590.1 AP2 domain containing protein, expressed AP2
LOC_Os07g03250.1 AP2-like ethylene-responsive transcription factor PLETHORA 2, putative, expressed AP2
LOC_Os07g10410.1 AP2 domain containing protein AP2
LOC_Os07g12510.1 AP2 domain containing protein, expressed AP2
LOC_Os07g13170.1 AP2 domain containing protein, expressed AP2
LOC_Os07g13170.2 AP2 domain containing protein, expressed AP2
LOC_Os07g22730.1 AP2 domain containing protein, expressed AP2
LOC_Os07g22770.1 AP2 domain containing protein, expressed AP2
LOC_Os07g38750.1 AP2 domain containing protein AP2
LOC_Os07g42510.1 AP2 domain containing protein, expressed AP2
LOC_Os07g47330.1 AP2 domain containing protein, expressed AP2
LOC_Os07g47790.1 AP2 domain containing protein, expressed AP2
LOC_Os07g47790.2 AP2 domain containing protein, expressed AP2
LOC_Os08g07440.1 AP2 domain containing protein, expressed AP2
LOC_Os08g07700.1 AP2 domain containing protein, expressed AP2
LOC_Os08g27220.1 AP2 domain containing protein AP2
LOC_Os08g31580.1 ethylene-responsive transcription factor, putative, expressed AP2
LOC_Os08g34360.1 AP2 domain containing protein, expressed AP2
LOC_Os08g35240.1 AP2 domain containing protein AP2
LOC_Os08g36920.1 AP2 domain containing protein, expressed AP2
LOC_Os08g41030.1 AP2 domain containing protein, expressed AP2
LOC_Os08g42550.1 AP2 domain containing protein, expressed AP2
LOC_Os08g43200.1 dehydration-responsive element-binding protein, putative, expressed AP2
LOC_Os08g43210.1 AP2 domain containing protein, expressed AP2
LOC_Os08g44960.1 AP2 domain containing protein AP2
LOC_Os08g45110.1 AP2 domain containing protein, expressed AP2
LOC_Os09g11460.1 AP2 domain containing protein, expressed AP2
LOC_Os09g11460.2 AP2 domain containing protein, expressed AP2
LOC_Os09g11480.1 AP2 domain containing protein, expressed AP2
LOC_Os09g11480.2 AP2 domain containing protein, expressed AP2
LOC_Os09g13940.1 AP2 domain containing protein, expressed AP2
LOC_Os09g13940.2 AP2 domain containing protein, expressed AP2
LOC_Os09g13940.3 AP2 domain containing protein, expressed AP2
LOC_Os09g13940.4 AP2 domain containing protein, expressed AP2
LOC_Os09g20350.1 ethylene-responsive transcription factor, putative, expressed AP2
LOC_Os09g25600.1 AP2 domain containing protein, expressed AP2
LOC_Os09g26420.1 AP2 domain containing protein, expressed AP2
LOC_Os09g26420.2 AP2 domain containing protein, expressed AP2
LOC_Os09g26420.3 AP2 domain containing protein, expressed AP2
LOC_Os09g26420.4 AP2 domain containing protein, expressed AP2
LOC_Os09g26420.5 AP2 domain containing protein, expressed AP2
LOC_Os09g28440.1 AP2 domain containing protein, expressed AP2
LOC_Os09g35010.1 dehydration-responsive element-binding protein, putative, expressed AP2
LOC_Os09g35020.1 AP2 domain containing protein, expressed AP2
LOC_Os09g35030.1 dehydration-responsive element-binding protein, putative, expressed AP2
LOC_Os09g39810.1 AP2 domain containing protein AP2
LOC_Os09g39850.1 AP2 domain containing protein AP2
LOC_Os10g22600.1 ethylene-responsive transcription factor, putative, expressed AP2
LOC_Os10g25170.1 AP2 domain containing protein, expressed AP2
LOC_Os10g26590.1 AP2 domain containing protein AP2
LOC_Os10g30840.1 AP2 domain containing protein AP2
LOC_Os10g38000.1 dehydration-responsive element-binding protein, putative AP2
LOC_Os10g41130.1 AP2 domain containing protein, expressed AP2
LOC_Os10g41330.1 AP2 domain containing protein, expressed AP2
LOC_Os10g41330.2 AP2 domain containing protein, expressed AP2
LOC_Os11g03540.1 AP2 domain containing protein, expressed AP2
LOC_Os11g06770.1 ethylene-responsive transcription factor ERF110, putative, expressed AP2
LOC_Os11g06770.2 ethylene-responsive transcription factor ERF110, putative, expressed AP2
LOC_Os11g13840.1 AP2 domain containing protein, expressed AP2
LOC_Os11g19060.1 BABY BOOM 1, putative, expressed AP2
LOC_Os12g03290.1 AP2 domain containing protein, expressed AP2
LOC_Os12g39330.1 AP2 domain containing protein, expressed AP2
LOC_Os12g41030.1 AP2 domain containing protein AP2
LOC_Os12g41060.1 AP2 domain containing protein, expressed AP2

General references

Gutterson, N; Reuber, TL. 2004. Regulation of disease resistance pathways by AP2/ERF transcription factors. Curr. Opin. Plant Biol. 7(4):465-71 PUBMEDID:15231271
Liu, Y; Zhao, TJ; Liu, JM; Liu, WQ; Liu, Q; Yan, YB; Zhou, HM. 2006. The conserved Ala37 in the ERF/AP2 domain is essential for binding with the DRE element and the GCC box. FEBS Lett. 580(5):1303-8 PUBMEDID:16457823
Magnani, E; Sjölander, K; Hake, S. 2004. From endonucleases to transcription factors: evolution of the AP2 DNA binding domain in plants. Plant Cell 16(9):2265-77 PUBMEDID:15319480
Ohme-Takagi, M; Shinshi, H. 1995. Ethylene-inducible DNA binding proteins that interact with an ethylene-responsive element. Plant Cell 7(2):173-82 PUBMEDID:7756828
Riechmann, JL; Meyerowitz, EM. 1998. The AP2/EREBP family of plant transcription factors. Biol. Chem. 379(6):633-46 PUBMEDID:9687012
Shigyo, M; Hasebe, M; Ito, M. 2006. Molecular evolution of the AP2 subfamily. Gene 366(2):256-65 PUBMEDID:16388920
Shigyo, M; Ito, M. 2004. Analysis of gymnosperm two-AP2-domain-containing genes. Dev. Genes Evol. 214(3):105-14 PUBMEDID:14986134
Weigel, D. 1995. The APETALA2 domain is related to a novel type of DNA binding domain. Plant Cell 7(4):388-9 PUBMEDID:7773013

Specific references

Chen, JQ; Dong, Y; Wang, YJ; Liu, Q; Zhang, JS; Chen, SY. 2003. An AP2/EREBP-type transcription-factor gene from rice is cold-inducible and encodes a nuclear-localized protein. Theor. Appl. Genet. 107(6):972-9 PUBMEDID:12844217
Ito, Y; Katsura, K; Maruyama, K; Taji, T; Kobayashi, M; Seki, M; Shinozaki, K; Yamaguchi-Shinozaki, K. 2006. Functional Analysis of Rice DREB1/CBF-type Transcription Factors Involved in Cold-responsive Gene Expression in Transgenic Rice. Plant Cell Physiol. 47(1):141-53 PUBMEDID:16284406
Shen, H; Wang, ZY. 2004. Expressional analysis of an EREBP transcription factor gene OsEBP-89 in rice. Acta Biochim. Biophys. Sin. (Shanghai) 36(1):21-6 PUBMEDID:14732870
Yang, HJ; Shen, H; Chen, L; Xing, YY; Wang, ZY; Zhang, JL; Hong, MM. 2002. The OsEBP-89 gene of rice encodes a putative EREBP transcription factor and is temporally expressed in developing endosperm and intercalary meristem. Plant Mol. Biol. 50(3):379-91 PUBMEDID:12369615