Plant Transcription factor database - Universität Potsdam
version: 3.0

Sorghum bicolor ARF Family


Guilfoyle et al. 1998: Auxin response factors or ARFs are a recently discovered family of transcription factors that bind with specificity to auxin response elements (AuxREs) in promoters of primary or early auxin-responsive genes. ARFs have an amino-terminal DNA-binding domain related to the carboxyl-terminal DNA-binding domain in the maize transactivator VIVIPAROUS1. All but one ARF identified to date contain a carboxyl-terminal protein-protein interaction domain that forms a putative amphipathic alpha-helix. A similar carboxyl-terminal protein-protein interaction domain is found in the Aux/IAA class of auxin-inducible proteins. Some ARFs contain transcriptional activation domains, while others contain repression domains. ARFs appear to play a pivotal role in auxin-regulated gene expression of primary response genes.

Members of this family
  SHOULD possess Auxin_resp domain

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for this family. The data reported by Remington et al. 2004 for A. thaliana were taken as gold standard.

The gold standard reported 23 members for this family, 21 of which are present in ArabTFDB, giving a PPV of 0.95. Two additional members not present in ArabTFDB might be false negatives, giving a Sensitivity of 0.91.

This family is also present in:


There are 25 gene models in this family

Gene modelDescriptionDomains
144563 estExt_fgenesh1_pm.C_chr_40676 Auxin_resp B3
145934 estExt_fgenesh1_pm.C_chr_80330 AUX_IAA Auxin_resp B3
4157335 gw1.2.17760.1 Auxin_resp B3
4759565 estExt_Genewise1.C_chr_55377 AUX_IAA Auxin_resp B3
4768603 estExt_Genewise1.C_chr_97121 Auxin_resp B3
4771745 estExt_Genewise1.C_chr_108051 Auxin_resp B3
4832325 e_gw1.6.16287.1 Auxin_resp B3
4877095 estExt_Genewise1Plus.C_chr_30067 Auxin_resp B3
4880038 estExt_Genewise1Plus.C_chr_38921 Auxin_resp B3
4889466 estExt_Genewise1Plus.C_chr_68346 AUX_IAA Auxin_resp B3
4893272 estExt_Genewise1Plus.C_chr_86436 Auxin_resp B3
4895791 estExt_Genewise1Plus.C_chr_97671 Auxin_resp B3
4976857 fgenesh1_pg.C_chr_3003972 Auxin_resp B3
5003562 estExt_fgenesh1_pg.C_chr_40347 Auxin_resp B3
5031057 Sb10g006440 Auxin_resp B3
5032113 Sb10g027220 Auxin_resp B3
5042202 Sb06g022810 Auxin_resp B3
5048741 Sb01g019130 Auxin_resp B3
5053492 Sb03g030740 Auxin_resp B3
5054714 Sb04g004430 Auxin_resp B3
5055266 Sb04g022830 AUX_IAA Auxin_resp B3
5057241 Sb06g017490 AUX_IAA Auxin_resp B3
5058204 Sb06g033970 Auxin_resp B3
5059071 Sb07g027080 Auxin_resp B3
5062139 Sb10g027790 Auxin_resp B3

General references

Guilfoyle, TJ; Ulmasov, T; Hagen, G. 1998. The ARF family of transcription factors and their role in plant hormone-responsive transcription. Cell. Mol. Life Sci. 54(7):619-27 PUBMEDID:9711229
Ulmasov, T; Hagen, G; Guilfoyle, TJ. 1997. ARF1, a transcription factor that binds to auxin response elements. Science 276(5320):1865-8 PUBMEDID:9188533