Plant Transcription factor database - Universität Potsdam
version: 3.0

Arabidopsis thaliana ARID Family

Description

Kortschak et al. 2000: Members of the recently discovered ARID (AT-rich interaction domain) family of DNA-binding proteins are found in fungi and invertebrate and vertebrate metazoans. ARID-encoding genes are involved in a variety of biological processes including embryonic development, cell lineage gene regulation and cell cycle control. Although the specific roles of this domain and of ARID-containing proteins in transcriptional regulation are yet to be elucidated, they include both positive and negative transcriptional regulation and a likely involvement in the modification of chromatin structure.

Patsialou et al. 2005: The ARID (A-T Rich Interaction Domain) is a helix-turn-helix motif-based DNA-binding domain, conserved in all eukaryotes and diagnostic of a family that includes 15 distinct human proteins with important roles in development, tissue-specific gene expression and proliferation control. Most ARID family members have not been characterized with respect to their DNA-binding behavior, but it is already apparent that not all ARIDs conform to the pattern of binding AT-rich sequences

Members of this family
  SHOULD possess ARID domain

Domain alignments

This family is also present in:

References

There are 11 gene models in this family



Gene modelDescriptionDomains
AT1G04880.1 high mobility group (HMG1/2) family protein / ARID/BRIGHT DNA-binding domain-containing protein ARID HMG_box
AT1G20910.1 ARID/BRIGHT DNA-binding domain-containing protein ARID
AT1G55650.1 high mobility group (HMG1/2) family protein / ARID/BRIGHT DNA-binding domain-containing protein ARID HMG_box
AT1G76110.1 high mobility group (HMG1/2) family protein / ARID/BRIGHT DNA-binding domain-containing protein ARID HMG_box
AT1G76510.1 ARID/BRIGHT DNA-binding domain-containing protein ARID
AT1G76510.2 ARID/BRIGHT DNA-binding domain-containing protein ARID
AT2G17410.1 ARID/BRIGHT DNA-binding domain-containing protein ARID
AT2G46040.1 ARID/BRIGHT DNA-binding domain-containing protein / ELM2 domain-containing protein ARID ELM2
AT3G13350.1 high mobility group (HMG1/2) family protein / ARID/BRIGHT DNA-binding domain-containing protein ARID HMG_box
AT3G43240.1 ARID/BRIGHT DNA-binding domain-containing protein ARID
AT4G11400.1 ARID/BRIGHT DNA-binding domain-containing protein / ELM2 domain-containing protein / Myb-like DNA-binding domain-containing protein ARID ELM2

General references

Kortschak, RD; Tucker, PW; Saint, R. 2000. ARID proteins come in from the desert. Trends Biochem. Sci. 25(6):294-9 PUBMEDID:10838570
Patsialou, A; Wilsker, D; Moran, E. 2005. DNA-binding properties of ARID family proteins. Nucleic Acids Res. 33(1):66-80 PUBMEDID:15640446
Wilsker, D; Patsialou, A; Dallas, PB; Moran, E. 2002. ARID proteins: a diverse family of DNA binding proteins implicated in the control of cell growth, differentiation, and development. Cell Growth Differ. 13(3):95-106 PUBMEDID:11959810
Wilsker, D; Probst, L; Wain, HM; Maltais, L; Tucker, PW; Moran, E. 2005. Nomenclature of the ARID family of DNA-binding proteins. Genomics 86(2):242-51 PUBMEDID:15922553