Plant Transcription factor database - Universität Potsdam
version: 3.0

Oryza sativa subsp. indica AUX/IAA Family


Tiwari et al. 2004: Aux/IAA proteins are short-lived nuclear proteins that repress expression of primary/early auxin response genes in protoplast transfection assays. Repression is thought to result from Aux/IAA proteins dimerizing with auxin response factor (ARF) transcriptional activators that reside on auxin-responsive promoter elements, referred to as AuxREs. Most Aux/IAA proteins contain four conserved domains, designated domains I, II, III, and IV. Domain II and domains III and IV play roles in protein stability and dimerization, respectively. A clear function for domain I had not been established. Results reported here indicate that domain I in Aux/IAA proteins is an active repression domain that is transferable and dominant over activation domains. An LxLxL motif within domain I is important for conferring repression. The dominance of Aux/IAA repression domains over activation domains in ARF transcriptional activators provides a plausible explanation for the repression of auxin response genes via ARF-Aux/IAA dimerization on auxin-responsive promoters.

Members of this family
  SHOULD possess AUX_IAA domain
  SHOULD NOT possess Auxin_resp B3 domains

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for this family. The data reported by Remington et al. 2004 for A. thaliana were taken as gold standard.

The gold standard reported 29 members for this family, 28 of which are present in ArabTFDB, giving a PPV of 1.00. One additional member not present in ArabTFDB might be a false negative, giving a Sensitivity of 0.97.

This family is also present in:


There are 30 gene models in this family

Gene modelDescriptionDomains
OsIBCD000527 Chr01_797,546,,,1,546, AUX_IAA
OsIBCD000591 Chr01_886,711,,,1,711, AUX_IAA
OsIBCD000843 Chr01_1240,801,,,1,801, AUX_IAA
OsIBCD001221 Chr01_1791,585,,,1,585, AUX_IAA
OsIBCD002890 Chr01_4550,735,,,1,735, AUX_IAA
OsIBCD003255 Chr01_5071,960,,,1,960, AUX_IAA
OsIBCD005604 Chr02_1264,903,,,1,903, AUX_IAA
OsIBCD008284 Chr02_5573,870,,,1,870, AUX_IAA Rhodanese
OsIBCD008302 Chr02_5592,543,,,1,543, AUX_IAA
OsIBCD008407 Chr02_5724,807,,,1,807, AUX_IAA
OsIBCD011298 Chr03_4329,420,,,1,420, AUX_IAA
OsIBCD011302 Chr03_4333,681,,,1,681, AUX_IAA
OsIBCD011305 Chr03_4337,285,,,1,285, AUX_IAA
OsIBCD011941 Chr03_5326,711,,,1,711, AUX_IAA
OsIBCD012266 Chr03_5782,588,,,1,588, AUX_IAA
OsIBCD016639 Chr05_745,597,,,1,597, AUX_IAA
OsIBCD016696 Chr05_857,1569,,,1,1569, AUX_IAA
OsIBCD017019 Chr05_1416,774,,,1,774, AUX_IAA
OsIBCD018645 Chr05_4166,879,,,1,879, AUX_IAA
OsIBCD018861 Chr05_4461,966,,,1,966, AUX_IAA
OsIBCD020446 Chr06_2113,591,,,1,591, AUX_IAA
OsIBCD020543 Chr06_2337,504,,,1,504, AUX_IAA
OsIBCD021277 Chr06_3660,585,,,1,585, AUX_IAA
OsIBCD022551 Chr07_678,822,,,1,822, AUX_IAA
OsIBCD022757 Chr07_1036,612,,,1,612, AUX_IAA
OsIBCD024776 Chr08_95,741,,,1,741, AUX_IAA
OsIBCD029180 Chr09_2928,423,,,1,423, AUX_IAA
OsIBCD032217 Chr11_974,435,,,1,435, AUX_IAA
OsIBCD035577 Chr12_3025,834,,,1,834, AUX_IAA
OsIBCD035578 Chr12_3027,594,,,1,594, AUX_IAA

General references

Liscum, E; Reed, JW. 2002. Genetics of Aux/IAA and ARF action in plant growth and development. Plant Mol. Biol. 49(3-4):387-400 PUBMEDID:12036262
Tiwari, SB; Hagen, G; Guilfoyle, TJ. 2004. Aux/IAA proteins contain a potent transcriptional repression domain. Plant Cell 16(2):533-43 PUBMEDID:14742873
Tiwari, SB; Wang, XJ; Hagen, G; Guilfoyle, TJ. 2001. AUX/IAA proteins are active repressors, and their stability and activity are modulated by auxin. Plant Cell 13(12):2809-22 PUBMEDID:11752389