Plant Transcription factor database - Universität Potsdam
version: 3.0

Zea mays AUX/IAA Family

Description

Tiwari et al. 2004: Aux/IAA proteins are short-lived nuclear proteins that repress expression of primary/early auxin response genes in protoplast transfection assays. Repression is thought to result from Aux/IAA proteins dimerizing with auxin response factor (ARF) transcriptional activators that reside on auxin-responsive promoter elements, referred to as AuxREs. Most Aux/IAA proteins contain four conserved domains, designated domains I, II, III, and IV. Domain II and domains III and IV play roles in protein stability and dimerization, respectively. A clear function for domain I had not been established. Results reported here indicate that domain I in Aux/IAA proteins is an active repression domain that is transferable and dominant over activation domains. An LxLxL motif within domain I is important for conferring repression. The dominance of Aux/IAA repression domains over activation domains in ARF transcriptional activators provides a plausible explanation for the repression of auxin response genes via ARF-Aux/IAA dimerization on auxin-responsive promoters.

Members of this family
  SHOULD possess AUX_IAA domain
  SHOULD NOT possess Auxin_resp B3 domains

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for this family. The data reported by Remington et al. 2004 for A. thaliana were taken as gold standard.

The gold standard reported 29 members for this family, 28 of which are present in ArabTFDB, giving a PPV of 1.00. One additional member not present in ArabTFDB might be a false negative, giving a Sensitivity of 0.97.

This family is also present in:

References

There are 93 gene models in this family



Gene modelDescriptionDomains
GRMZM2G000158_P01 AUX_IAA
GRMZM2G000158_P02 AUX_IAA
GRMZM2G000158_P03 AUX_IAA
GRMZM2G000158_P04 AUX_IAA
GRMZM2G001799_P01 AUX_IAA
GRMZM2G004696_P01 AUX_IAA
GRMZM2G013158_P01 AUX_IAA
GRMZM2G018479_P01 AUX_IAA
GRMZM2G018479_P02 AUX_IAA
GRMZM2G030465_P01 AUX_IAA
GRMZM2G030465_P02 AUX_IAA
GRMZM2G034840_P02 AUX_IAA
GRMZM2G035465_P01 AUX_IAA
GRMZM2G035465_P02 AUX_IAA
GRMZM2G035465_P03 AUX_IAA
GRMZM2G035465_P04 AUX_IAA
GRMZM2G035465_P05 AUX_IAA
GRMZM2G037368_P01 AUX_IAA
GRMZM2G048131_P01 AUX_IAA
GRMZM2G051769_P01 AUX_IAA
GRMZM2G057067_P01 AUX_IAA
GRMZM2G057067_P02 AUX_IAA
GRMZM2G057067_P03 AUX_IAA
GRMZM2G057067_P04 AUX_IAA
GRMZM2G059544_P01 AUX_IAA
GRMZM2G060022_P01 AUX_IAA
GRMZM2G060022_P02 AUX_IAA
GRMZM2G060022_P03 AUX_IAA
GRMZM2G066155_P01 AUX_IAA
GRMZM2G066155_P02 AUX_IAA
GRMZM2G074427_P01 AUX_IAA
GRMZM2G074427_P02 AUX_IAA
GRMZM2G074742_P01 AUX_IAA
GRMZM2G077356_P01 AUX_IAA
GRMZM2G079114_P02 AUX_IAA
GRMZM2G079200_P01 AUX_IAA
GRMZM2G079200_P02 AUX_IAA
GRMZM2G079200_P03 AUX_IAA
GRMZM2G079957_P01 AUX_IAA
GRMZM2G079957_P02 AUX_IAA
GRMZM2G079957_P04 AUX_IAA
GRMZM2G084993_P01 AUX_IAA
GRMZM2G096540_P01 AUX_IAA
GRMZM2G097279_P01 AUX_IAA
GRMZM2G097279_P02 AUX_IAA
GRMZM2G103589_P01 AUX_IAA
GRMZM2G103589_P02 AUX_IAA
GRMZM2G104176_P01 AUX_IAA
GRMZM2G115357_P01 AUX_IAA
GRMZM2G115357_P02 AUX_IAA
GRMZM2G121309_P01 AUX_IAA
GRMZM2G122622_P01 AUX_IAA
GRMZM2G126422_P02 AUX_IAA
GRMZM2G128421_P01 AUX_IAA
GRMZM2G130953_P01 AUX_IAA
GRMZM2G130953_P02 AUX_IAA
GRMZM2G130953_P03 AUX_IAA
GRMZM2G130953_P04 AUX_IAA
GRMZM2G134517_T01_P01 AUX_IAA
GRMZM2G137363_P01 AUX_IAA
GRMZM2G137692_P01 AUX_IAA
GRMZM2G137692_P02 AUX_IAA
GRMZM2G137692_P03 AUX_IAA
GRMZM2G138268_P01 AUX_IAA
GRMZM2G138268_P02 AUX_IAA
GRMZM2G138268_P03 AUX_IAA
GRMZM2G141205_T01_P01 AUX_IAA
GRMZM2G141751_P01 AUX_IAA
GRMZM2G141751_P02 AUX_IAA
GRMZM2G142768_P01 AUX_IAA
GRMZM2G142768_P02 AUX_IAA
GRMZM2G143850_P01 AUX_IAA
GRMZM2G147243_P01 AUX_IAA
GRMZM2G147243_P02 AUX_IAA
GRMZM2G149449_P01 AUX_IAA
GRMZM2G152796_P01 AUX_IAA
GRMZM2G152796_P02 AUX_IAA
GRMZM2G155082_P01 AUX_IAA
GRMZM2G159285_P01 AUX_IAA
GRMZM2G159285_P02 AUX_IAA
GRMZM2G163848_P01 AUX_IAA
GRMZM2G163848_P02 AUX_IAA
GRMZM2G163848_P03 AUX_IAA
GRMZM2G163848_P04 AUX_IAA
GRMZM2G163848_P05 AUX_IAA
GRMZM2G163848_P06 AUX_IAA
GRMZM2G163848_P07 AUX_IAA
GRMZM2G167794_P01 AUX_IAA
GRMZM2G168699_P01 AUX_IAA
GRMZM2G168699_P02 AUX_IAA
GRMZM2G172569_P01 AUX_IAA
GRMZM2G172569_P02 AUX_IAA
GRMZM2G180050_P01 AUX_IAA

General references

Liscum, E; Reed, JW. 2002. Genetics of Aux/IAA and ARF action in plant growth and development. Plant Mol. Biol. 49(3-4):387-400 PUBMEDID:12036262
Tiwari, SB; Hagen, G; Guilfoyle, TJ. 2004. Aux/IAA proteins contain a potent transcriptional repression domain. Plant Cell 16(2):533-43 PUBMEDID:14742873
Tiwari, SB; Wang, XJ; Hagen, G; Guilfoyle, TJ. 2001. AUX/IAA proteins are active repressors, and their stability and activity are modulated by auxin. Plant Cell 13(12):2809-22 PUBMEDID:11752389