Plant Transcription factor database - Universität Potsdam
version: 3.0

Populus trichocarpa BES1 Family


Yin et al. 2005: Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1, accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo. BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Members of this family
  SHOULD possess DUF822 domain

Domain alignments

This family is also present in:


There are 12 gene models in this family

Gene modelDescriptionDomains
235185 gw1.XI.3165.1 DUF822
275891 gw1.178.81.1 DUF822
414016 gw1.III.1119.1 DUF822 Glyco_hydro_14
550259 eugene3.00012700 DUF822
551922 eugene3.00021237 DUF822
555627 eugene3.00040340 DUF822
591830 eugene3.00400175 DUF822
711150 estExt_Genewise1_v1.C_LG_II3010 DUF822
719435 estExt_Genewise1_v1.C_LG_VII3341 DUF822
777919 fgenesh4_pg.C_LG_XVI001161 DUF822
805972 fgenesh4_pm.C_LG_XI000247 DUF822
827108 estExt_fgenesh4_pg.C_570205 DUF822

General references

Li, L; Deng, XW. 2005. It runs in the family: regulation of brassinosteroid signaling by the BZR1-BES1 class of transcription factors. Trends Plant Sci. 10(6):266-8 PUBMEDID:15949759
Vert, G; Nemhauser, JL; Geldner, N; Hong, F; Chory, J. 2005. Molecular mechanisms of steroid hormone signaling in plants. Annu. Rev. Cell Dev. Biol. 21:177-201 PUBMEDID:16212492
Yin, Y; Vafeados, D; Tao, Y; Yoshida, S; Asami, T; Chory, J. 2005. A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis. Cell 120(2):249-59 PUBMEDID:15680330