Plant Transcription factor database - Universität Potsdam
version: 3.0

Arabidopsis thaliana C2C2-Dof Family

Description

Yanagisawa. 2004: Dof (DNA-binding with one finger) domain proteins are plant-specific transcription factors with a highly conserved DNA-binding domain, which presumably includes a single C(2)-C(2) zinc finger. During the past decade, numerous Dof domain proteins have been identified in both monocots and dicots including maize, barley, wheat, rice, tobacco, Arabidopsis, pumpkin, potato, and pea. Biochemical, molecular biological and molecular genetic analyses revealed that Dof domain proteins function as a transcriptional activator or a repressor involved in diverse plant-specific biological processes. Although more physiological roles of Dof domain proteins would be elucidated in future because of numerous Dof domain proteins in plants, it is already evident that the Dof domain proteins play critical roles as transcriptional regulators in plant growth and development.

Members of this family
  SHOULD possess zf-Dof domain

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for this family. The data reported by Lijavetzky et al. 2003 for A. thaliana were taken as gold standard.

The gold standard reported 36 members for this family, 35 of which are present in ArabTFDB, giving a PPV of 0.97. One additional member not present in ArabTFDB might be a false negative, giving a Sensitivity of 0.97.

This family is also present in:

References

There are 45 gene models in this family



Gene modelDescriptionDomains
AT1G07640.1 OBP2 (OBF BINDING PROTEIN 2); DNA binding / transcription factor zf-Dof
AT1G07640.2 OBP2 (OBF BINDING PROTEIN 2); DNA binding / transcription factor zf-Dof
AT1G07640.3 OBP2 (OBF BINDING PROTEIN 2); DNA binding zf-Dof
AT1G21340.1 Dof-type zinc finger domain-containing protein zf-Dof
AT1G26790.1 Dof-type zinc finger domain-containing protein zf-Dof
AT1G28310.1 Dof-type zinc finger domain-containing protein zf-Dof
AT1G28310.2 Dof-type zinc finger domain-containing protein zf-Dof
AT1G29160.1 Dof-type zinc finger domain-containing protein zf-Dof
AT1G47655.1 Dof-type zinc finger domain-containing protein zf-Dof
AT1G51700.1 ADOF1 (Arabidopsis dof zinc finger protein 1); DNA binding / transcription factor zf-Dof
AT1G64620.1 Dof-type zinc finger domain-containing protein zf-Dof
AT1G69570.1 Dof-type zinc finger domain-containing protein zf-Dof
AT2G28510.1 Dof-type zinc finger domain-containing protein zf-Dof
AT2G28810.1 Dof-type zinc finger domain-containing protein zf-Dof
AT2G34140.1 Dof-type zinc finger domain-containing protein zf-Dof
AT2G37590.1 Dof-type zinc finger domain-containing protein zf-Dof
AT2G46590.1 DAG2 (DOF AFFECTING GERMINATION 2); DNA binding / transcription factor zf-Dof
AT2G46590.2 DAG2 (DOF AFFECTING GERMINATION 2); DNA binding zf-Dof
AT3G21270.1 ADOF2 (Arabidopsis dof zinc finger protein 2); DNA binding / transcription factor zf-Dof
AT3G45610.1 Dof-type zinc finger domain-containing protein zf-Dof
AT3G47500.1 CDF3 (CYCLING DOF FACTOR 3); DNA binding / protein binding / transcription factor zf-Dof
AT3G50410.1 OBP1 (OBF BINDING PROTEIN 1); DNA binding / transcription factor zf-Dof
AT3G52440.1 Dof-type zinc finger domain-containing protein zf-Dof
AT3G55370.1 OBP3 (OBF-BINDING PROTEIN 3); DNA binding / transcription factor zf-Dof
AT3G55370.2 OBP3 (OBF-BINDING PROTEIN 3); DNA binding zf-Dof
AT3G61850.1 DAG1 (DOF AFFECTING GERMINATION 1); DNA binding / transcription factor zf-Dof
AT3G61850.2 DAG1 (DOF AFFECTING GERMINATION 1); DNA binding / transcription factor zf-Dof
AT3G61850.3 DAG1 (DOF AFFECTING GERMINATION 1) zf-Dof
AT3G61850.4 DAG1 (DOF AFFECTING GERMINATION 1) zf-Dof
AT4G00940.1 Dof-type zinc finger domain-containing protein zf-Dof
AT4G21030.1 Dof-type zinc finger domain-containing protein zf-Dof
AT4G21040.1 Dof-type zinc finger domain-containing protein zf-Dof
AT4G21050.1 Dof-type zinc finger domain-containing protein zf-Dof
AT4G21080.1 Dof-type zinc finger domain-containing protein zf-Dof
AT4G24060.1 Dof-type zinc finger domain-containing protein zf-Dof
AT4G38000.1 Dof-type zinc finger domain-containing protein zf-Dof
AT5G02460.1 Dof-type zinc finger domain-containing protein zf-Dof
AT5G39660.1 CDF2 (CYCLING DOF FACTOR 2); DNA binding / protein binding / transcription factor zf-Dof
AT5G39660.2 CDF2 (CYCLING DOF FACTOR 2); DNA binding / transcription factor zf-Dof
AT5G60200.1 Dof-type zinc finger domain-containing protein zf-Dof
AT5G60850.1 OBP4 (OBF BINDING PROTEIN 4); DNA binding / transcription factor zf-Dof
AT5G62430.1 CDF1 (CYCLING DOF FACTOR 1); DNA binding / protein binding / transcription factor zf-Dof
AT5G62940.1 Dof-type zinc finger domain-containing protein zf-Dof
AT5G65590.1 Dof-type zinc finger domain-containing protein zf-Dof
AT5G66940.1 Dof-type zinc finger domain-containing protein zf-Dof

General references

Moreno-Risueno, MA; Martínez, M; Vicente-Carbajosa, J; Carbonero, P. 2006. The family of DOF transcription factors: from green unicellular algae to vascular plants. Mol Genet Genomics PUBMEDID:17180359
Shigyo, M; Tabei, N; Yoneyama, T; Yanagisawa, S. 2006. Evolutional processes during the formation of the plant-specific Dof transcription factor family. Plant Cell Physiol PUBMEDID:17132629
Umemura, Y; Ishiduka, T; Yamamoto, R; Esaka, M. 2004. The Dof domain, a zinc finger DNA-binding domain conserved only in higher plants, truly functions as a Cys2/Cys2 Zn finger domain. Plant J. 37(5):741-9 PUBMEDID:14871313
Yanagisawa, S. 1997. Dof DNA-binding domains of plant transcription factors contribute to multiple protein-protein interactions. Eur. J. Biochem. 250(2):403-10 PUBMEDID:9428691
Yanagisawa, S. 2002. The Dof family of plant transcription factors. Trends Plant Sci. 7(12):555-60 PUBMEDID:12475498
Yanagisawa, S. 2004. Dof domain proteins: plant-specific transcription factors associated with diverse phenomena unique to plants. Plant Cell Physiol. 45(4):386-91 PUBMEDID:15111712
Yanagisawa, S; Schmidt, RJ. 1999. Diversity and similarity among recognition sequences of Dof transcription factors. Plant J. 17(2):209-14 PUBMEDID:10074718

Specific references

Lijavetzky, D; Carbonero, P; Vicente-Carbajosa, J. 2003. Genome-wide comparative phylogenetic analysis of the rice and Arabidopsis Dof gene families. BMC Evol. Biol. 3:17 PUBMEDID:12877745