Plant Transcription factor database - Universität Potsdam
version: 3.0

Sorghum bicolor Coactivator p15 Family


Kretzschmar et al. 1994: Functional deletion analyses revealed a bipartite structure of p15 comprising an amino-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain. We provide evidence that activity of p15 is controlled by protein kinases that target the regulatory domain. Structural and functional similarities, including sequence homology to domains essential for cofactor function, cofactor activity, promiscuity with respect to transcriptional activators, and interactions with components of the basal transcription machinery, relate this novel cellular cofactor to viral immediate-early transcriptional regulators.

Members of this family
  SHOULD possess PC4 domain

Domain alignments

This family is also present in:


There are 2 gene models in this family

Gene modelDescriptionDomains
5002433 estExt_fgenesh1_pg.C_chr_32663 PC4
5055252 Sb04g022580 PC4

General references

Kretzschmar, M; Kaiser, K; Lottspeich, F; Meisterernst, M. 1994. A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators. Cell 78(3):525-34 PUBMEDID:8062392