Zea mays Coactivator p15 Family

Description

Kretzschmar et al. 1994: Functional deletion analyses revealed a bipartite structure of p15 comprising an amino-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain. We provide evidence that activity of p15 is controlled by protein kinases that target the regulatory domain. Structural and functional similarities, including sequence homology to domains essential for cofactor function, cofactor activity, promiscuity with respect to transcriptional activators, and interactions with components of the basal transcription machinery, relate this novel cellular cofactor to viral immediate-early transcriptional regulators.

Domain alignments

This family is also present in:

• Cyanidioschyzon merolae
• Galdieria sulphuraria
• Micromonas pusilla CCMP1545
• Micromonas sp. RCC299
• Ostreococcus lucimarinus
• Ostreococcus tauri
• Chlamydomonas reinhardtii
• Chlorella sp. NC64A
• Coccomyxa sp. C-169
• Physcomitrella patens
• Selaginella moellendorffii
• Oryza sativa subsp. indica
• Oryza sativa subsp. japonica
• Sorghum bicolor
• Arabidopsis lyrata
• Arabidopsis thaliana
• Carica papaya
• Populus trichocarpa
• Vitis vinifera

References

There are 7 gene models in this family