version: 3.0

Chlorella sp. NC64A E2F-DP Family

Description

E2F-DP transcription factors are key components of the cyclin D/retinoblastoma/E2F pathway, they regulate the expression of genes required for G1/S transition and S-phase progression.

Members of this family
SHOULD possess E2F_TDP domain

Domain alignments

This family is also present in:

Cyanidioschyzon merolae
Galdieria sulphuraria
Micromonas pusilla CCMP1545
Micromonas sp. RCC299
Ostreococcus lucimarinus
Ostreococcus tauri
Chlamydomonas reinhardtii
Coccomyxa sp. C-169
Physcomitrella patens
Selaginella moellendorffii
Oryza sativa subsp. indica
Oryza sativa subsp. japonica
Sorghum bicolor
Zea mays
Arabidopsis lyrata
Arabidopsis thaliana
Carica papaya
Populus trichocarpa
Vitis vinifera

References

There are 3 gene models in this family

Gene model	Description	Domains
138406	IGS.gm_20_00155	E2F_TDP
138629	IGS.gm_21_00108	E2F_TDP
15459	gw1.2.505.1	E2F_TDP

General references

de Jager, SM; Menges, M; Bauer, UM; Murra, JA. 2001. Arabidopsis E2F1 binds a sequence present in the promoter of S-phase-regulated gene AtCDC6 and is a member of a multigene family with differential activities. Plant Mol. Biol. 47(4):555-68 PUBMEDID:11669580
Zheng, N; Fraenkel, E; Pabo, CO; Pavletich, NP. 1999. Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP. Genes Dev. 13(6):666-74 PUBMEDID:10090723