Tian et al. 2004: Members of the GRAS gene family encode transcriptional regulators that have diverse functions in plant growth and development such as gibberellin signal transduction, root radial patterning, axillary meristem formation, phytochrome A signal transduction, and gametogenesis.
The Sensitivity and Positive Predictive Value (PPV) were assessed for this family. The data reported by Bolle 2004 for A. thaliana were taken as gold standard.
The gold standard reported 33 members for this family, 32 of which are present in ArabTFDB, giving a PPV of 0.97. One additional member not present in ArabTFDB might be a false negative, giving a Sensitivity of 0.97.
Bolle, C. 2004. The role of GRAS proteins in plant signal transduction and development. Planta 218(5):683-92 PUBMEDID:14760535 Richards, DE; Peng, J; Harberd, NP. 2000. Plant GRAS and metazoan STATs: one family? Bioessays 22(6):573-7 PUBMEDID:10842311
Itoh, H; Shimada, A; Ueguchi-Tanaka, M; Kamiya, N; Hasegawa, Y; Ashikari, M; Matsuoka, M. 2005. Overexpression of a GRAS protein lacking the DELLA domain confers altered gibberellin responses in rice. Plant J. 44(4):669-79 PUBMEDID:16262715 Tian, C; Wan, P; Sun, S; Li, J; Chen, M. 2004. Genome-wide analysis of the GRAS gene family in rice and Arabidopsis. Plant Mol. Biol. 54(4):519-32 PUBMEDID:15316287