Plant Transcription factor database - Universität Potsdam
version: 3.0

Oryza sativa subsp. japonica GRF Family

Description

Kim et al. 2003: Previously, we identified a novel rice gene, GROWTH-REGULATING FACTOR1 (OsGRF1), which encodes a putative transcription factor that appears to play a regulatory role in stem elongation. We now describe the GRF gene family of Arabidopsis thaliana (AtGRF), which comprises nine members. The deduced AtGRF proteins contain the same characteristic regions--the QLQ (Gln, Leu, Gln) and WRC (Trp, Arg, Cys) domains--as do OsGRF1 and related proteins in rice, as well as features indicating a function in transcriptional regulation. Most of the AtGRF genes are strongly expressed in actively growing and developing tissues, such as shoot tips, flower buds, and roots, but weakly in mature stem and leaf tissues. Overexpression of AtGRF1 and AtGRF2 resulted in larger leaves and cotyledons, as well as in delayed bolting of the inflorescence stem when compared to wild-type plants. In contrast, triple insertional null mutants of AtGRF1-AtGRF3 had smaller leaves and cotyledons, whereas single mutants displayed no changes in phenotype and double mutants displayed only minor ones. The alteration of leaf growth in overexpressors and triple mutants was based on an increase or decrease in cell size, respectively. These results indicate that AtGRF proteins play a role in the regulation of cell expansion in leaf and cotyledon tissues.

Members of this family
  SHOULD possess QLQ WRC domains

Domain alignments

This family is also present in:

References

There are 19 gene models in this family



Gene modelDescriptionDomains
LOC_Os02g45570.1 growth regulating factor protein, putative, expressed QLQ WRC
LOC_Os02g45570.2 growth regulating factor protein, putative, expressed QLQ WRC
LOC_Os02g47280.1 growth-regulating factor, putative, expressed GRF QLQ WRC
LOC_Os02g47280.2 growth-regulating factor, putative, expressed GRF QLQ WRC
LOC_Os02g53690.1 growth regulating factor protein, putative, expressed GRF QLQ WRC
LOC_Os03g47140.1 growth regulating factor protein, putative, expressed GRF QLQ WRC
LOC_Os03g51970.1 growth-regulating factor, putative, expressed GRF QLQ WRC
LOC_Os04g48510.1 growth regulating factor protein, putative, expressed GRF QLQ WRC
LOC_Os04g51190.1 growth-regulating factor, putative, expressed GRF QLQ WRC
LOC_Os04g51190.2 growth-regulating factor, putative, expressed GRF QLQ WRC
LOC_Os04g51190.3 growth-regulating factor, putative, expressed GRF QLQ WRC
LOC_Os06g02560.1 growth-regulating factor, putative, expressed GRF QLQ WRC
LOC_Os06g02560.2 growth-regulating factor, putative, expressed GRF QLQ WRC
LOC_Os06g02560.3 growth-regulating factor, putative, expressed GRF QLQ WRC
LOC_Os06g10310.1 growth regulating factor protein, putative, expressed GRF QLQ WRC
LOC_Os07g28430.1 growth regulating factor protein, putative, expressed QLQ WRC
LOC_Os11g35030.1 growth regulating factor protein, putative, expressed GRF QLQ WRC
LOC_Os12g29980.1 growth regulating factor protein, putative, expressed GRF QLQ WRC
LOC_Os12g29980.2 growth regulating factor protein, putative, expressed GRF QLQ WRC

General references

Kim, JH; Choi, D; Kende, H. 2003. The AtGRF family of putative transcription factors is involved in leaf and cotyledon growth in Arabidopsis. Plant J. 36(1):94-104 PUBMEDID:12974814

Specific references

Choi, D; Kim, JH; Kende, H. 2004. Whole genome analysis of the OsGRF gene family encoding plant-specific putative transcription activators in rice (Oryza sativa L.). Plant Cell Physiol. 45(7):897-904 PUBMEDID:15295073