Plant Transcription factor database - Universität Potsdam
version: 3.0

Arabidopsis thaliana GeBP Family


Curaba et al. 2003: Trichomes of Arabidopsis are single-celled epidermal hair that are a useful model for studying plant cell fate determination. Trichome initiation requires the activity of the GLABROUS1 (GL1) gene whose expression in epidermal and trichome cells is dependent on the presence of a 3'-cis-regulatory element. Using a one-hybrid screen, we have isolated a cDNA, which encodes for a protein, GL1 enhancer binding protein (GeBP), that binds this regulatory element in yeast and in vitro. GeBP and its three homologues in Arabidopsis share two regions: a central region with no known motifs and a C-terminal region with a putative leucine-zipper motif. We show that both regions are necessary for trans-activation in yeast. A translational fusion with the Yellow Fluorescent Protein (YFP) indicates that GeBP is a nuclear protein whose localization is restricted to, on average, 3-5 subnuclear foci that might correspond to nucleoli. Transcriptional fusion with the GUS reporter indicates that GeBP is mainly expressed in vegetative meristematic tissues and in very young leaf primordia. We looked at GeBP expression in plants mutated in or misexpressing KNAT1, a KNOX gene, expressed in the shoot apical meristem and downregulated in leaf founder cells, and found that GeBP transcript level is regulated by KNAT1 suggesting that KNAT1 is a transcriptional activator of GeBP. This regulation suggests that GeBP is acting as a repressor of leaf cell fate.

Members of this family
  SHOULD possess DUF573 domain

Domain alignments

This family is also present in:


There are 20 gene models in this family

Gene modelDescriptionDomains
AT1G11510.1 DNA-binding storekeeper protein-related DUF573
AT1G44810.1 transcription regulator DUF573
AT1G55950.1 similar to DNA-binding storekeeper protein-related [Arabidopsis thaliana] (TAIR:AT2G01370.1); similar to unknown [Populus trichocarpa] (GB:ABK93310.1); contains InterPro domain Protein of unknown function DUF573 (InterPro:IPR007592) DUF573
AT1G61730.1 DNA-binding storekeeper protein-related DUF573
AT1G66420.1 transcription regulator DUF573
AT2G01370.1 DNA-binding storekeeper protein-related DUF573
AT2G25650.1 DNA-binding storekeeper protein-related DUF573
AT2G36340.1 DNA-binding storekeeper protein-related DUF573
AT3G04930.1 transcription regulator DUF573
AT4G00130.1 similar to transcription regulator [Arabidopsis thaliana] (TAIR:AT4G25210.1); similar to unknown [Populus trichocarpa] (GB:ABK93310.1); contains InterPro domain Protein of unknown function DUF573 (InterPro:IPR007592) DUF573
AT4G00232.1 similar to unknown protein [Arabidopsis thaliana] (TAIR:AT5G41765.1); contains InterPro domain Protein of unknown function DUF573 (InterPro:IPR007592) DUF573
AT4G00238.1 DNA-binding storekeeper protein-related DUF573
AT4G00250.1 DNA-binding storekeeper protein-related DUF573
AT4G00270.1 DNA-binding storekeeper protein-related DUF573
AT4G00390.1 transcription regulator DUF573
AT4G00610.1 DNA-binding storekeeper protein-related DUF573
AT4G01260.1 transcription regulator DUF573
AT4G25210.1 transcription regulator DUF573
AT5G14280.1 DNA-binding storekeeper protein-related DUF573
AT5G28040.1 transcription regulator DUF573

General references

Chevalier, F; Perazza, D; Laporte, F; Le Hénanff, G; Hornitschek, P; Bonneville, JM; Herzog, M; Vachon, G. 2008. GeBP and GeBP-like proteins are noncanonical leucine-zipper transcription factors that regulate cytokinin response in Arabidopsis. Plant Physiol. 146(3):1142-54 PUBMEDID:18162594
Curaba, J; Herzog, M; Vachon, G. 2003. GeBP, the first member of a new gene family in Arabidopsis, encodes a nuclear protein with DNA-binding activity and is regulated by KNAT1. Plant J. 33(2):305-17 PUBMEDID:12535344