Plant Transcription factor database - Universität Potsdam
version: 3.0

Arabidopsis lyrata Jumonji Family


Noh et al. 2004: Flowering in Arabidopsis thaliana is controlled by multiple pathways, including the photoperiod pathway and the FLOWERING LOCUS C (FLC)-dependent pathway. Here, we report that a pair of related jumonji-class transcription factors, EARLY FLOWERING 6 (ELF6) and RELATIVE OF EARLY FLOWERING 6 (REF6), play divergent roles in the regulation of Arabidopsis flowering. ELF6 acts as a repressor in the photoperiod pathway, whereas REF6, which has the highest similarity to ELF6, is an FLC repressor. Ectopic expression studies and expression pattern analyses show that ELF6 and REF6 have different cellular roles and are also regulated differentially despite their sequence similarities. Repression of FLC expression by REF6 accompanies histone modifications in FLC chromatin, indicating that the transcriptional regulatory activity of this class of proteins includes chromatin remodeling. This report demonstrates the in vivo functions of this class of proteins in higher eukaryotes.

Members of this family
  SHOULD possess JmjC JmjN domains
  SHOULD NOT possess Alfin-like ARID zf-C2H2 domains

Domain alignments

This family is also present in:


There are 18 gene models in this family

Gene modelDescriptionDomains
331156 fgenesh1_pm.C_scaffold_8000499 JmjC
332532 fgenesh1_pm.C_scaffold_8001875 JmjC
334149 fgenesh1_pg.C_scaffold_1000714 FYRC FYRN JmjC JmjN zf-C5HC2
336188 fgenesh1_pg.C_scaffold_1002753 FYRC FYRN JmjC JmjN zf-C5HC2
359220 fgenesh1_pg.C_scaffold_60000001 JmjC
470987 fgenesh2_kg.1__941__AT1G09060.2 JmjC WRC
471347 fgenesh2_kg.1__1301__AT1G11950.1 JmjC
478089 fgenesh2_kg.3__790__AT3G07610.1 JmjC
482914 fgenesh2_kg.4__1974__AT2G38950.1 JmjC JmjN zf-C5HC2
487465 fgenesh2_kg.6__599__AT5G06550.1 F-box JmjC
490470 fgenesh2_kg.6__3604__AT4G00990.1 JmjC
492821 fgenesh2_kg.7__2254__AT4G20400.1 FYRC FYRN JmjC JmjN zf-C5HC2
868831 Al_scaffold_0004_994 JmjC JmjN zf-C5HC2
869817 Al_scaffold_0004_1980 FYRC FYRN JmjC JmjN zf-C5HC2
875696 Al_scaffold_0002_290 JmjC
895721 scaffold_202795.1 F-box JmjC
914534 scaffold_702276.1 JmjC WRC
916732 scaffold_800132.1 JmjC JmjN zf-C5HC2

General references

Balciunas, D; Ronne, H. 2000. Evidence of domain swapping within the jumonji family of transcription factors. Trends Biochem. Sci. 25(6):274-6 PUBMEDID:10838566
Kim, TG; Kraus, JC; Chen, J; Lee, Y. 2003. JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor. J. Biol. Chem. 278(43):42247-55 PUBMEDID:12890668
Takeuchi, T; Watanabe, Y; Takano-Shimizu, T; Kondo, S. 2006. Roles of jumonji and jumonji family genes in chromatin regulation and development. Dev Dyn PUBMEDID:16715513