Plant Transcription factor database - Universität Potsdam
version: 3.0

Chlorella sp. NC64A Jumonji Family

Description

Noh et al. 2004: Flowering in Arabidopsis thaliana is controlled by multiple pathways, including the photoperiod pathway and the FLOWERING LOCUS C (FLC)-dependent pathway. Here, we report that a pair of related jumonji-class transcription factors, EARLY FLOWERING 6 (ELF6) and RELATIVE OF EARLY FLOWERING 6 (REF6), play divergent roles in the regulation of Arabidopsis flowering. ELF6 acts as a repressor in the photoperiod pathway, whereas REF6, which has the highest similarity to ELF6, is an FLC repressor. Ectopic expression studies and expression pattern analyses show that ELF6 and REF6 have different cellular roles and are also regulated differentially despite their sequence similarities. Repression of FLC expression by REF6 accompanies histone modifications in FLC chromatin, indicating that the transcriptional regulatory activity of this class of proteins includes chromatin remodeling. This report demonstrates the in vivo functions of this class of proteins in higher eukaryotes.

Members of this family
  SHOULD possess JmjC JmjN domains
  SHOULD NOT possess Alfin-like ARID zf-C2H2 domains

Domain alignments

This family is also present in:

References

There are 11 gene models in this family



Gene modelDescriptionDomains
137703 IGS.gm_2_00170 F-box JmjC
137990 IGS.gm_2_00457 JmjC
139247 IGS.gm_24_00027 JmjC
139600 IGS.gm_25_00151 JmjC JmjN
139911 IGS.gm_27_00089 JmjC
144357 IGS.gm_7_00299 JmjC
144771 IGS.gm_8_00099 F-box JmjC
21253 e_gw1.5.214.1 JmjC
28921 e_gw1.78.1.1 JmjC
28922 e_gw1.78.3.1 JmjC
51859 fgenesh3_pg.C_scaffold_8000146 JmjC JmjN zf-C5HC2

General references

Balciunas, D; Ronne, H. 2000. Evidence of domain swapping within the jumonji family of transcription factors. Trends Biochem. Sci. 25(6):274-6 PUBMEDID:10838566
Kim, TG; Kraus, JC; Chen, J; Lee, Y. 2003. JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor. J. Biol. Chem. 278(43):42247-55 PUBMEDID:12890668
Takeuchi, T; Watanabe, Y; Takano-Shimizu, T; Kondo, S. 2006. Roles of jumonji and jumonji family genes in chromatin regulation and development. Dev Dyn PUBMEDID:16715513