Plant Transcription factor database - Universität Potsdam
version: 3.0

Coccomyxa sp. C-169 Jumonji Family


Noh et al. 2004: Flowering in Arabidopsis thaliana is controlled by multiple pathways, including the photoperiod pathway and the FLOWERING LOCUS C (FLC)-dependent pathway. Here, we report that a pair of related jumonji-class transcription factors, EARLY FLOWERING 6 (ELF6) and RELATIVE OF EARLY FLOWERING 6 (REF6), play divergent roles in the regulation of Arabidopsis flowering. ELF6 acts as a repressor in the photoperiod pathway, whereas REF6, which has the highest similarity to ELF6, is an FLC repressor. Ectopic expression studies and expression pattern analyses show that ELF6 and REF6 have different cellular roles and are also regulated differentially despite their sequence similarities. Repression of FLC expression by REF6 accompanies histone modifications in FLC chromatin, indicating that the transcriptional regulatory activity of this class of proteins includes chromatin remodeling. This report demonstrates the in vivo functions of this class of proteins in higher eukaryotes.

Members of this family
  SHOULD possess JmjC JmjN domains
  SHOULD NOT possess Alfin-like ARID zf-C2H2 domains

Domain alignments

This family is also present in:


There are 12 gene models in this family

Gene modelDescriptionDomains
17039 gw1.5.195.1 F-box JmjC
19092 gw1.12.326.1 JmjC
27437 e_gw1.4.851.1 JmjC zf-C5HC2
32439 e_gw1.16.119.1 JmjC
42215 estExt_Genewise1Plus.C_60067 JmjC JmjN
63560 GG.C169_S14_00229 JmjC
64886 GG.C169_S19_00135 JmjC
65689 GG.C169_S23_00049 JmjC
76374 fgeneshCV_pg.C_scaffold_18000161 JmjC
76451 fgeneshCV_pg.C_scaffold_19000003 CBS JmjC Voltage_CLC
76626 fgeneshCV_pg.C_scaffold_19000178 JmjC JmjN
77471 fgeneshCV_pg.C_scaffold_26000024 JmjC

General references

Balciunas, D; Ronne, H. 2000. Evidence of domain swapping within the jumonji family of transcription factors. Trends Biochem. Sci. 25(6):274-6 PUBMEDID:10838566
Kim, TG; Kraus, JC; Chen, J; Lee, Y. 2003. JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor. J. Biol. Chem. 278(43):42247-55 PUBMEDID:12890668
Takeuchi, T; Watanabe, Y; Takano-Shimizu, T; Kondo, S. 2006. Roles of jumonji and jumonji family genes in chromatin regulation and development. Dev Dyn PUBMEDID:16715513