Plant Transcription factor database - Universität Potsdam
version: 3.0

Ostreococcus lucimarinus Jumonji Family

Description

Noh et al. 2004: Flowering in Arabidopsis thaliana is controlled by multiple pathways, including the photoperiod pathway and the FLOWERING LOCUS C (FLC)-dependent pathway. Here, we report that a pair of related jumonji-class transcription factors, EARLY FLOWERING 6 (ELF6) and RELATIVE OF EARLY FLOWERING 6 (REF6), play divergent roles in the regulation of Arabidopsis flowering. ELF6 acts as a repressor in the photoperiod pathway, whereas REF6, which has the highest similarity to ELF6, is an FLC repressor. Ectopic expression studies and expression pattern analyses show that ELF6 and REF6 have different cellular roles and are also regulated differentially despite their sequence similarities. Repression of FLC expression by REF6 accompanies histone modifications in FLC chromatin, indicating that the transcriptional regulatory activity of this class of proteins includes chromatin remodeling. This report demonstrates the in vivo functions of this class of proteins in higher eukaryotes.

Members of this family
  SHOULD possess JmjC JmjN domains
  SHOULD NOT possess Alfin-like ARID zf-C2H2 domains

Domain alignments

This family is also present in:

References

There are 10 gene models in this family



Gene modelDescriptionDomains
12370 fgenesh1_pm.C_Chr_3000090 JmjC
17878 fgenesh1_pg.C_Chr_13000162 JmjC PHD PLU-1 zf-C5HC2
19230 fgenesh1_pg.C_Chr_21000073 JmjC PHD PLU-1 zf-C5HC2
25099 estExt_fgenesh1_pg.C_Chr_100017 JmjC
39523 e_gwEuk.1.392.1 JmjC
42117 e_gwEuk.17.96.1 JmjC
4533 gwEuk.3.330.1 JmjC
5502 gwEuk.8.318.1 JmjC zf-C5HC2
93634 ost_13_011_026 JmjC
94145 ost_21_004_034 JmjC

General references

Balciunas, D; Ronne, H. 2000. Evidence of domain swapping within the jumonji family of transcription factors. Trends Biochem. Sci. 25(6):274-6 PUBMEDID:10838566
Kim, TG; Kraus, JC; Chen, J; Lee, Y. 2003. JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor. J. Biol. Chem. 278(43):42247-55 PUBMEDID:12890668
Takeuchi, T; Watanabe, Y; Takano-Shimizu, T; Kondo, S. 2006. Roles of jumonji and jumonji family genes in chromatin regulation and development. Dev Dyn PUBMEDID:16715513