Ostreococcus tauri Jumonji Family
Description
Noh et al. 2004: Flowering in Arabidopsis thaliana is controlled by multiple pathways, including the photoperiod pathway and the FLOWERING LOCUS C (FLC)-dependent pathway. Here, we report that a pair of related jumonji-class transcription factors, EARLY FLOWERING 6 (ELF6) and RELATIVE OF EARLY FLOWERING 6 (REF6), play divergent roles in the regulation of Arabidopsis flowering. ELF6 acts as a repressor in the photoperiod pathway, whereas REF6, which has the highest similarity to ELF6, is an FLC repressor. Ectopic expression studies and expression pattern analyses show that ELF6 and REF6 have different cellular roles and are also regulated differentially despite their sequence similarities. Repression of FLC expression by REF6 accompanies histone modifications in FLC chromatin, indicating that the transcriptional regulatory activity of this class of proteins includes chromatin remodeling. This report demonstrates the in vivo functions of this class of proteins in higher eukaryotes.
Members of this familySHOULD possess JmjC JmjN domains
SHOULD NOT possess Alfin-like ARID zf-C2H2 domains
This family is also present in:
- Cyanidioschyzon merolae
- Galdieria sulphuraria
- Micromonas pusilla CCMP1545
- Micromonas sp. RCC299
- Ostreococcus lucimarinus
- Chlamydomonas reinhardtii
- Chlorella sp. NC64A
- Coccomyxa sp. C-169
- Physcomitrella patens
- Selaginella moellendorffii
- Oryza sativa subsp. indica
- Oryza sativa subsp. japonica
- Sorghum bicolor
- Zea mays
- Arabidopsis lyrata
- Arabidopsis thaliana
- Carica papaya
- Populus trichocarpa
- Vitis vinifera
There are 5 gene models in this family
General references
Balciunas, D; Ronne, H. 2000. Evidence of domain swapping within the jumonji family of transcription factors. Trends Biochem. Sci. 25(6):274-6 PUBMEDID:10838566Kim, TG; Kraus, JC; Chen, J; Lee, Y. 2003. JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor. J. Biol. Chem. 278(43):42247-55 PUBMEDID:12890668
Takeuchi, T; Watanabe, Y; Takano-Shimizu, T; Kondo, S. 2006. Roles of jumonji and jumonji family genes in chromatin regulation and development. Dev Dyn PUBMEDID:16715513
Design qRT-PCR primers using Quantprime