Plant Transcription factor database - Universität Potsdam
version: 3.0

Sorghum bicolor Jumonji Family


Noh et al. 2004: Flowering in Arabidopsis thaliana is controlled by multiple pathways, including the photoperiod pathway and the FLOWERING LOCUS C (FLC)-dependent pathway. Here, we report that a pair of related jumonji-class transcription factors, EARLY FLOWERING 6 (ELF6) and RELATIVE OF EARLY FLOWERING 6 (REF6), play divergent roles in the regulation of Arabidopsis flowering. ELF6 acts as a repressor in the photoperiod pathway, whereas REF6, which has the highest similarity to ELF6, is an FLC repressor. Ectopic expression studies and expression pattern analyses show that ELF6 and REF6 have different cellular roles and are also regulated differentially despite their sequence similarities. Repression of FLC expression by REF6 accompanies histone modifications in FLC chromatin, indicating that the transcriptional regulatory activity of this class of proteins includes chromatin remodeling. This report demonstrates the in vivo functions of this class of proteins in higher eukaryotes.

Members of this family
  SHOULD possess JmjC JmjN domains
  SHOULD NOT possess Alfin-like ARID zf-C2H2 domains

Domain alignments

This family is also present in:


There are 19 gene models in this family

Gene modelDescriptionDomains
4755021 estExt_Genewise1.C_chr_40122 JmjC
4841228 e_gw1.7.15293.1 JmjC
4859925 e_gw1.10.16825.1 JmjN
4865548 e_gw1.10.15729.1 JmjC PHD PLU-1 zf-C5HC2
4870547 estExt_Genewise1Plus.C_chr_18688 F-box JmjC
4878807 estExt_Genewise1Plus.C_chr_36420 JmjC
4885362 estExt_Genewise1Plus.C_chr_49649 AT_hook JmjC
4897240 estExt_Genewise1Plus.C_chr_102163 FYRC FYRN JmjC JmjN zf-C5HC2
4968757 fgenesh1_pg.C_chr_2000073 JmjC JmjN zf-C5HC2
4991161 fgenesh1_pg.C_chr_9000889 FYRN JmjC JmjN zf-C5HC2
4995736 fgenesh1_pg.C_scaffold_11000016 JmjC JmjN
5038896 Sb04g031040 JmjC zf-C5HC2
5044195 Sb07g027795 JmjC
5048555 Sb01g015210 JmjC
5048994 Sb01g027940 JmjC JmjN zf-C5HC2
5049432 Sb01g035540 JmjC WRC
5051139 Sb02g024010 JmjC
5056092 Sb04g036630 FYRC FYRN JmjC JmjN zf-C5HC2
5056683 Sb05g022250 F-box JmjC

General references

Balciunas, D; Ronne, H. 2000. Evidence of domain swapping within the jumonji family of transcription factors. Trends Biochem. Sci. 25(6):274-6 PUBMEDID:10838566
Kim, TG; Kraus, JC; Chen, J; Lee, Y. 2003. JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor. J. Biol. Chem. 278(43):42247-55 PUBMEDID:12890668
Takeuchi, T; Watanabe, Y; Takano-Shimizu, T; Kondo, S. 2006. Roles of jumonji and jumonji family genes in chromatin regulation and development. Dev Dyn PUBMEDID:16715513