Plant Transcription factor database - Universität Potsdam
version: 3.0

Oryza sativa subsp. japonica LOB Family

Description

Husbands et al. 2007: Conserved in a variety of evolutionarily divergent plant species, LOB DOMAIN (LBD) genes define a large, plant-specific family of largely unknown function. LBD genes have been implicated in a variety of developmental processes in plants, although to date, relatively few members have been assigned functions. LBD proteins have previously been predicted to be transcription factors, however supporting evidence has only been circumstantial. To address the biochemical function of LBD proteins, we identified a 6-bp consensus motif recognized by a wide cross-section of LBD proteins, and showed that LATERAL ORGAN BOUNDARIES (LOB), the founding member of the family, is a transcriptional activator in yeast. Thus, the LBD genes encode a novel class of DNA-binding transcription factors. Post-translational regulation of transcription factors is often crucial for control of gene expression. In our study, we demonstrate that members of the basic helix-loop-helix (bHLH) family of transcription factors are capable of interacting with LOB. The expression patterns of bHLH048 and LOB overlap at lateral organ boundaries. Interestingly, the interaction of bHLH048 with LOB results in reduced affinity of LOB for the consensus DNA motif. Thus, our studies suggest that bHLH048 post-translationally regulates the function of LOB at lateral organ boundaries.

Members of this family
  SHOULD possess DUF260 domain

Domain alignments

This family is also present in:

References

There are 39 gene models in this family



Gene modelDescriptionDomains
LOC_Os01g03890.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os01g07480.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os01g07480.2 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os01g14030.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os01g32770.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os01g39040.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os01g39070.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os01g39150.1 DUF260 domain containing protein, putative DUF260
LOC_Os01g39160.1 DUF260 domain containing protein, putative DUF260
LOC_Os01g39180.1 DUF260 domain containing protein, putative DUF260
LOC_Os01g39220.1 DUF260 domain containing protein, putative DUF260
LOC_Os01g56530.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os01g60960.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os01g66590.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os01g66590.2 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os01g66590.3 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os02g48270.1 DUF260 domain containing protein, putative DUF260
LOC_Os02g57490.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os03g05500.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os03g05510.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os03g14270.1 DUF260 domain containing protein, putative DUF260
LOC_Os03g17810.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os03g33090.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os03g41330.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os03g41600.1 DUF260 domain containing protein, putative DUF260
LOC_Os03g45750.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os03g57670.1 DUF260 domain containing protein, putative DUF260
LOC_Os05g03160.1 DUF260 domain containing protein, putative DUF260
LOC_Os05g07270.1 DUF260 domain containing protein, putative DUF260
LOC_Os05g27980.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os05g34450.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os07g40000.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os08g06659.1 expressed protein DUF260
LOC_Os08g31080.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os08g44940.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os09g19950.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os10g07510.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os11g01550.1 DUF260 domain containing protein, putative, expressed DUF260
LOC_Os12g01550.1 DUF260 domain containing protein, putative, expressed DUF260

General references

Husbands, A; Bell, EM; Shuai, B; Smith, HM; Springer, PS. 2007. LATERAL ORGAN BOUNDARIES defines a new family of DNA-binding transcription factors and can interact with specific bHLH proteins. Nucleic Acids Res. 35(19):6663-71 PUBMEDID:17913740