Plant Transcription factor database - Universität Potsdam
version: 3.0

Populus trichocarpa LOB Family


Husbands et al. 2007: Conserved in a variety of evolutionarily divergent plant species, LOB DOMAIN (LBD) genes define a large, plant-specific family of largely unknown function. LBD genes have been implicated in a variety of developmental processes in plants, although to date, relatively few members have been assigned functions. LBD proteins have previously been predicted to be transcription factors, however supporting evidence has only been circumstantial. To address the biochemical function of LBD proteins, we identified a 6-bp consensus motif recognized by a wide cross-section of LBD proteins, and showed that LATERAL ORGAN BOUNDARIES (LOB), the founding member of the family, is a transcriptional activator in yeast. Thus, the LBD genes encode a novel class of DNA-binding transcription factors. Post-translational regulation of transcription factors is often crucial for control of gene expression. In our study, we demonstrate that members of the basic helix-loop-helix (bHLH) family of transcription factors are capable of interacting with LOB. The expression patterns of bHLH048 and LOB overlap at lateral organ boundaries. Interestingly, the interaction of bHLH048 with LOB results in reduced affinity of LOB for the consensus DNA motif. Thus, our studies suggest that bHLH048 post-translationally regulates the function of LOB at lateral organ boundaries.

Members of this family
  SHOULD possess DUF260 domain

Domain alignments

This family is also present in:


There are 57 gene models in this family

Gene modelDescriptionDomains
202430 gw1.IX.2895.1 DUF260
208472 gw1.V.3873.1 DUF260
218784 gw1.VII.3089.1 DUF260
225513 gw1.X.210.1 DUF260
228473 gw1.X.3170.1 DUF260
241912 gw1.XIII.2161.1 DUF260
244069 gw1.XIV.812.1 DUF260
250303 gw1.XIX.2703.1 DUF260
252251 gw1.XV.1687.1 DUF260
253705 gw1.XV.3141.1 DUF260
292131 gw1.6210.2.1 DUF260
292818 gw1.64.470.1 DUF260
409906 gw1.II.1241.1 DUF260
409907 gw1.II.1242.1 DUF260
410466 gw1.II.1801.1 DUF260
411706 gw1.II.3041.1 DUF260
415707 gw1.VI.80.1 DUF260
419520 gw1.VIII.948.1 DUF260
419701 gw1.VIII.1129.1 DUF260
423166 gw1.XII.1626.1 DUF260
423258 gw1.XII.1718.1 DUF260
424396 gw1.87.10.1 DUF260
559669 eugene3.00051284 DUF260
562869 eugene3.00070807 DUF260
571894 eugene3.00131258 DUF260
572115 eugene3.00140160 DUF260
573102 eugene3.00141147 DUF260
574365 eugene3.00190839 DUF260
577952 eugene3.00180176 DUF260
580249 eugene3.01190031 DUF260
582780 eugene3.01420087 DUF260
592770 eugene3.00440105 DUF260
641633 grail3.0054008101 DUF260
646183 grail3.0089001701 DUF260
646851 grail3.0018050401 DUF260
649671 grail3.0001067101 DUF260
656281 grail3.0010003901 DUF260
656362 grail3.0010011101 DUF260
659394 grail3.0022002901 DUF260
659480 grail3.0022010801 DUF260
666365 grail3.0005001801 DUF260
720235 estExt_Genewise1_v1.C_LG_VIII0894 DUF260
752465 fgenesh4_pg.C_LG_I002068 DUF260
758936 fgenesh4_pg.C_LG_IV000564 DUF260
770335 fgenesh4_pg.C_LG_X001825 DUF260
772709 fgenesh4_pg.C_LG_XII000484 DUF260
772939 fgenesh4_pg.C_LG_XII000714 DUF260
786915 fgenesh4_pg.C_scaffold_187000022 DUF260
798071 fgenesh4_pm.C_LG_I001074 DUF260
798505 fgenesh4_pm.C_LG_II000194 DUF260
801067 fgenesh4_pm.C_LG_V000159 DUF260
810965 fgenesh4_pm.C_scaffold_123000043 DUF260
814988 estExt_fgenesh4_pg.C_LG_I0705 DUF260
822368 estExt_fgenesh4_pg.C_LG_X1642 DUF260
822538 estExt_fgenesh4_pg.C_LG_X1964 DUF260
823880 estExt_fgenesh4_pg.C_LG_XIV0088 DUF260
831441 estExt_fgenesh4_pm.C_LG_V0239 DUF260

General references

Husbands, A; Bell, EM; Shuai, B; Smith, HM; Springer, PS. 2007. LATERAL ORGAN BOUNDARIES defines a new family of DNA-binding transcription factors and can interact with specific bHLH proteins. Nucleic Acids Res. 35(19):6663-71 PUBMEDID:17913740