Plant Transcription factor database - Universität Potsdam
version: 3.0

Vitis vinifera LOB Family

Description

Husbands et al. 2007: Conserved in a variety of evolutionarily divergent plant species, LOB DOMAIN (LBD) genes define a large, plant-specific family of largely unknown function. LBD genes have been implicated in a variety of developmental processes in plants, although to date, relatively few members have been assigned functions. LBD proteins have previously been predicted to be transcription factors, however supporting evidence has only been circumstantial. To address the biochemical function of LBD proteins, we identified a 6-bp consensus motif recognized by a wide cross-section of LBD proteins, and showed that LATERAL ORGAN BOUNDARIES (LOB), the founding member of the family, is a transcriptional activator in yeast. Thus, the LBD genes encode a novel class of DNA-binding transcription factors. Post-translational regulation of transcription factors is often crucial for control of gene expression. In our study, we demonstrate that members of the basic helix-loop-helix (bHLH) family of transcription factors are capable of interacting with LOB. The expression patterns of bHLH048 and LOB overlap at lateral organ boundaries. Interestingly, the interaction of bHLH048 with LOB results in reduced affinity of LOB for the consensus DNA motif. Thus, our studies suggest that bHLH048 post-translationally regulates the function of LOB at lateral organ boundaries.

Members of this family
  SHOULD possess DUF260 domain

Domain alignments

This family is also present in:

References

There are 45 gene models in this family



Gene modelDescriptionDomains
GSVIVP00000068001 DUF260
GSVIVP00001451001 DUF260
GSVIVP00003846001 DUF260
GSVIVP00007498001 DUF260
GSVIVP00007499001 DUF260
GSVIVP00008636001 DUF260
GSVIVP00008637001 DUF260
GSVIVP00009328001 DUF260
GSVIVP00009702001 DUF260
GSVIVP00009703001 DUF260
GSVIVP00009704001 DUF260
GSVIVP00014946001 DUF260
GSVIVP00016010001 DUF260 Oleosin
GSVIVP00016552001 DUF260
GSVIVP00017674001 DUF260
GSVIVP00018244001 DUF260
GSVIVP00018245001 DUF260
GSVIVP00018247001 DUF260
GSVIVP00018249001 DUF260
GSVIVP00018250001 DUF260
GSVIVP00018253001 DUF260
GSVIVP00018255001 DUF260
GSVIVP00018256001 DUF260
GSVIVP00018258001 DUF260
GSVIVP00018260001 DUF260
GSVIVP00018263001 DUF260
GSVIVP00018439001 DUF260
GSVIVP00018685001 DUF260 F-box
GSVIVP00019643001 DUF260
GSVIVP00020677001 DUF260
GSVIVP00020863001 DUF260 PPR
GSVIVP00023965001 DUF260
GSVIVP00024029001 DUF260
GSVIVP00024478001 DUF260
GSVIVP00024480001 DUF260
GSVIVP00025687001 DUF260
GSVIVP00026357001 DUF260
GSVIVP00026359001 DUF260
GSVIVP00029332001 DUF260
GSVIVP00029359001 DUF260
GSVIVP00029404001 DUF260
GSVIVP00030342001 DUF260
GSVIVP00035531001 DUF260
GSVIVP00038218001 DUF260
GSVIVP00038501001 DUF260

General references

Husbands, A; Bell, EM; Shuai, B; Smith, HM; Springer, PS. 2007. LATERAL ORGAN BOUNDARIES defines a new family of DNA-binding transcription factors and can interact with specific bHLH proteins. Nucleic Acids Res. 35(19):6663-71 PUBMEDID:17913740