Plant Transcription factor database - Universität Potsdam
version: 3.0

Zea mays LOB Family

Description

Husbands et al. 2007: Conserved in a variety of evolutionarily divergent plant species, LOB DOMAIN (LBD) genes define a large, plant-specific family of largely unknown function. LBD genes have been implicated in a variety of developmental processes in plants, although to date, relatively few members have been assigned functions. LBD proteins have previously been predicted to be transcription factors, however supporting evidence has only been circumstantial. To address the biochemical function of LBD proteins, we identified a 6-bp consensus motif recognized by a wide cross-section of LBD proteins, and showed that LATERAL ORGAN BOUNDARIES (LOB), the founding member of the family, is a transcriptional activator in yeast. Thus, the LBD genes encode a novel class of DNA-binding transcription factors. Post-translational regulation of transcription factors is often crucial for control of gene expression. In our study, we demonstrate that members of the basic helix-loop-helix (bHLH) family of transcription factors are capable of interacting with LOB. The expression patterns of bHLH048 and LOB overlap at lateral organ boundaries. Interestingly, the interaction of bHLH048 with LOB results in reduced affinity of LOB for the consensus DNA motif. Thus, our studies suggest that bHLH048 post-translationally regulates the function of LOB at lateral organ boundaries.

Members of this family
  SHOULD possess DUF260 domain

Domain alignments

This family is also present in:

References

There are 88 gene models in this family



Gene modelDescriptionDomains
AC218000.3_FGP020 DUF260
GRMZM2G005363_P01 DUF260
GRMZM2G006980_P01 DUF260
GRMZM2G011385_P01 DUF260
GRMZM2G014649_P01 DUF260
GRMZM2G014649_P02 DUF260
GRMZM2G014649_P03 DUF260
GRMZM2G017319_P01 DUF260
GRMZM2G021095_P01 DUF260
GRMZM2G025758_P01 DUF260
GRMZM2G025989_P01 DUF260
GRMZM2G026167_P01 DUF260
GRMZM2G030505_P01 DUF260
GRMZM2G044150_P01 DUF260
GRMZM2G044902_P01 DUF260
GRMZM2G044902_P02 DUF260
GRMZM2G044902_P03 DUF260
GRMZM2G053580_P01 DUF260
GRMZM2G055770_P01 DUF260
GRMZM2G059329_P01 DUF260
GRMZM2G059567_P01 DUF260
GRMZM2G060197_P01 DUF260
GRMZM2G060544_P01 DUF260
GRMZM2G062252_P01 DUF260
GRMZM2G070459_P01 DUF260
GRMZM2G073044_P01 DUF260
GRMZM2G074706_P01 DUF260
GRMZM2G075499_P01 DUF260
GRMZM2G075559_P01 DUF260
GRMZM2G076327_P01 DUF260
GRMZM2G078734_P01 DUF260
GRMZM2G079185_P01 DUF260
GRMZM2G079768_P01 DUF260
GRMZM2G083315_T01_P01 DUF260
GRMZM2G085339_T01_P01 DUF260
GRMZM2G086814_P01 DUF260
GRMZM2G086900_P01 DUF260
GRMZM2G087099_P01 DUF260
GRMZM2G087099_P02 DUF260
GRMZM2G091084_P01 DUF260
GRMZM2G091910_P01 DUF260
GRMZM2G092483_P01 DUF260
GRMZM2G092483_P02 DUF260
GRMZM2G092517_P01 DUF260
GRMZM2G092542_P01 DUF260
GRMZM2G092542_P02 DUF260
GRMZM2G095260_P01 DUF260
GRMZM2G095982_P01 DUF260
GRMZM2G096064_P01 DUF260
GRMZM2G097539_P01 DUF260
GRMZM2G098135_P01 DUF260
GRMZM2G099733_P01 DUF260
GRMZM2G106759_T01_P01 DUF260
GRMZM2G108564_P01 DUF260
GRMZM2G110913_P01 DUF260
GRMZM2G117488_P01 DUF260
GRMZM2G118250_P03 DUF260
GRMZM2G118250_P04 DUF260
GRMZM2G118250_P05 DUF260
GRMZM2G118250_P06 DUF260
GRMZM2G121487_P01 DUF260
GRMZM2G126550_P01 DUF260
GRMZM2G132667_P01 DUF260
GRMZM2G132693_P01 DUF260
GRMZM2G133806_P01 DUF260
GRMZM2G133806_P02 DUF260
GRMZM2G133806_P03 DUF260
GRMZM2G133806_P04 DUF260
GRMZM2G133806_P05 DUF260
GRMZM2G135660_P01 DUF260
GRMZM2G139487_P01 DUF260
GRMZM2G140368_P01 DUF260
GRMZM2G140368_P02 DUF260
GRMZM2G145568_P01 DUF260
GRMZM2G146216_P01 DUF260
GRMZM2G150594_P01 DUF260
GRMZM2G154320_P01 DUF260
GRMZM2G163222_P01 DUF260
GRMZM2G165805_P01 DUF260
GRMZM2G176026_P01 DUF260
GRMZM2G177110_P01 DUF260
GRMZM2G180319_P01 DUF260
GRMZM2G180319_P02 DUF260
GRMZM2G180895_P01 DUF260
GRMZM2G180895_P02 DUF260
GRMZM2G180900_P01 DUF260
GRMZM2G180900_P02 DUF260
GRMZM2G180900_P03 DUF260

General references

Husbands, A; Bell, EM; Shuai, B; Smith, HM; Springer, PS. 2007. LATERAL ORGAN BOUNDARIES defines a new family of DNA-binding transcription factors and can interact with specific bHLH proteins. Nucleic Acids Res. 35(19):6663-71 PUBMEDID:17913740