Plant Transcription factor database - Universität Potsdam
version: 3.0

Populus trichocarpa LUG Family

Description

Conner & Liu. 2000: Regulation of homeotic gene expression is critical for proper developmental patterns in both animals and plants. LEUNIG is a key regulator of the Arabidopsis floral homeotic gene AGAMOUS. Mutations in LEUNIG cause ectopic AGAMOUS mRNA expression in the outer two whorls of a flower, leading to homeotic transformations of floral organ identity as well as loss of floral organs. We isolated the LEUNIG gene by using a map-based approach and showed that LEUNIG encodes a glutamine-rich protein with seven WD repeats and is similar in motif structure to a class of functionally related transcriptional corepressors including Tup1 from yeast and Groucho from Drosophila. The nuclear localization of LEUNIG-GFP is consistent with a role of LEUNIG as a transcriptional regulator. The detection of LEUNIG mRNA in all floral whorls at the time of their inception suggests that the restricted activity of LEUNIG in the outer two floral whorls must depend on interactions with other spatially restricted factors or on posttranslational regulation. Our finding suggests that both animals and plants use similar repressor proteins to regulate critical developmental processes.

Members of this family
  SHOULD possess LUFS domain

Domain alignments

This family is also present in:

References

There are 5 gene models in this family



Gene modelDescriptionDomains
750825 fgenesh4_pg.C_LG_I000428 LUFS LisH WD40
778982 fgenesh4_pg.C_LG_XVIII000350 LUFS LisH SSDP WD40
817567 estExt_fgenesh4_pg.C_LG_III1493 LUFS LisH WD40
819573 estExt_fgenesh4_pg.C_LG_VI1732 LUFS LisH SSDP WD40
830572 estExt_fgenesh4_pm.C_LG_II1120 LUFS LisH WD40

General references

Conner, J; Liu, Z. 2000. LEUNIG, a putative transcriptional corepressor that regulates AGAMOUS expression during flower development. Proc. Natl. Acad. Sci. U.S.A. 97(23):12902-7 PUBMEDID:11058164