Plant Transcription factor database - Universität Potsdam
version: 3.0

Arabidopsis thaliana MADS Family

Description

Riechmann & Meyerowitz. 1997: The MADS domain (MCM1, AGAMOUS, DEFICIENS, and SRF, serum response factor) is a conserved DNA-binding/dimerization region present in a variety of transcription factors from different kingdoms. MADS box genes represent a large multigene family in vascular plants. In angiosperms, many of the genes of the MADS family are involved in different steps of flower development, most notably in the determination of floral meristem and organ identity. The roles that MADS box genes play, however, are not restricted to control the development of the plant reproductive structures. The genetic, molecular, and biochemical basis of the action of the MADS domain proteins in the plant life cycle are reviewed here.

Members of this family
  SHOULD possess SRF-TF domain

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for this family. The data reported by Parenicova et al. 2003 for A. thaliana were taken as gold standard.

The gold standard reported 108 members for this family, 99 of which are present in ArabTFDB, giving a PPV of 0.95. Nine additional members not present in ArabTFDB might be false negatives, giving a Sensitivity of 0.92.

This family is also present in:

References

There are 132 gene models in this family



Gene modelDescriptionDomains
AT1G01530.1 AGL28 (AGAMOUS-LIKE 28); DNA binding / transcription factor SRF-TF
AT1G17310.1 MADS-box protein (AGL100) SRF-TF
AT1G18750.1 AGL65; DNA binding / transcription factor SRF-TF
AT1G22130.1 AGL104; DNA binding / transcription factor SRF-TF
AT1G22590.2 AGL87 SRF-TF
AT1G24260.1 SEP3 (SEPALLATA3); transcription factor K-box SRF-TF
AT1G24260.2 SEP3 (SEPALLATA3); transcription factor K-box SRF-TF
AT1G26310.1 CAL (CAULIFLOWER); DNA binding / transcription factor K-box SRF-TF
AT1G28450.1 AGL58; DNA binding / transcription factor SRF-TF
AT1G28460.1 AGL59; DNA binding / transcription factor SRF-TF
AT1G29962.1 AGL64; transcription factor SRF-TF
AT1G31140.1 AGL63 (AGAMOUS-LIKE 63); DNA binding / transcription factor SRF-TF
AT1G31630.1 AGL86; DNA binding / transcription factor SRF-TF
AT1G31640.1 AGL92; DNA binding / transcription factor SRF-TF
AT1G46408.1 AGL97; DNA binding / transcription factor SRF-TF
AT1G47760.1 AGL102; DNA binding / transcription factor SRF-TF
AT1G48150.1 MADS-box protein (AGL74 ) SRF-TF
AT1G59810.1 AGL50; transcription factor SRF-TF
AT1G60040.1 AGL49; transcription factor SRF-TF
AT1G60880.1 AGL56 (AGAMOUS LIKE-56); DNA binding / transcription factor SRF-TF
AT1G60920.1 AGL55 (AGAMOUS-LIKE 55); DNA binding / transcription factor SRF-TF
AT1G65300.1 PHE2 (PHERES2); DNA binding / transcription factor SRF-TF
AT1G65330.1 PHE1 (PHERES1); DNA binding / transcription factor SRF-TF
AT1G65360.1 AGL23; DNA binding / transcription factor SRF-TF
AT1G69120.1 AP1 (APETALA1); DNA binding / transcription factor K-box SRF-TF
AT1G69540.1 AGL94; DNA binding / transcription factor SRF-TF
AT1G71692.1 AGL12 (AGAMOUS-LIKE 12); transcription factor K-box SRF-TF
AT1G72350.1 MADS-box protein (AGL60) SRF-TF
AT1G77080.2 MAF1 (MADS AFFECTING FLOWERING 1); transcription factor K-box SRF-TF
AT1G77080.4 MAF1 (MADS AFFECTING FLOWERING 1); transcription factor K-box SRF-TF
AT1G77950.1 AGL67; transcription factor SRF-TF
AT1G77950.2 AGL67 SRF-TF
AT1G77980.1 AGL66; transcription factor SRF-TF
AT2G03060.1 AGL30; DNA binding / transcription factor SRF-TF
AT2G03060.2 AGL30 SRF-TF
AT2G03710.1 SEP4 (SEPALLATA4); DNA binding / transcription factor K-box SRF-TF
AT2G03710.2 SEP4 (SEPALLATA4); DNA binding / transcription factor K-box SRF-TF
AT2G03710.3 SEP4 (SEPALLATA4); DNA binding K-box SRF-TF
AT2G14210.1 ANR1; DNA binding / transcription factor K-box SRF-TF
AT2G22540.1 SVP (SHORT VEGETATIVE PHASE); transcription factor K-box SRF-TF
AT2G22630.1 AGL17 (AGAMOUS-LIKE 17); transcription factor K-box SRF-TF
AT2G24840.1 AGL61; DNA binding / transcription factor SRF-TF
AT2G26320.1 AGL33; DNA binding / transcription factor SRF-TF
AT2G28700.1 AGL46; DNA binding / transcription factor SRF-TF
AT2G34440.1 AGL29; transcription factor SRF-TF
AT2G40210.1 AGL48; transcription factor SRF-TF
AT2G42830.1 SHP2 (SHATTERPROOF 2); transcription factor K-box SRF-TF
AT2G42830.2 SHP2 (SHATTERPROOF 2); transcription factor K-box SRF-TF
AT2G45650.1 AGL6 (AGAMOUS LIKE-6); DNA binding / transcription factor K-box SRF-TF
AT2G45660.1 AGL20 (AGAMOUS-LIKE 20); transcription factor K-box SRF-TF
AT3G02310.1 SEP2 (SEPALLATA2); DNA binding / transcription factor K-box SRF-TF
AT3G04100.1 AGL57; DNA binding / transcription factor SRF-TF
AT3G05860.1 MADS-box protein (AGL45) SRF-TF
AT3G05860.2 MADS-box protein (AGL45) SRF-TF
AT3G05860.3 MADS-box protein (AGL45) SRF-TF
AT3G18650.1 AGL103 (AGAMOUS-LIKE 103); transcription factor SRF-TF
AT3G30260.1 MADS-box protein (AGL79) K-box SRF-TF
AT3G54340.1 AP3 (APETALA 3); DNA binding / transcription factor K-box SRF-TF
AT3G57230.1 AGL16 (AGAMOUS-LIKE 16); transcription factor K-box SRF-TF
AT3G57230.2 AGL16 (AGAMOUS-LIKE 16) K-box SRF-TF
AT3G57390.1 AGL18 (AGAMOUS-LIKE 18); transcription factor K-box SRF-TF
AT3G58780.1 SHP1 (SHATTERPROOF 1); DNA binding / transcription factor K-box SRF-TF
AT3G58780.2 SHP1 (SHATTERPROOF 1) K-box SRF-TF
AT3G61120.1 AGL13 (AGAMOUS-LIKE 13); DNA binding / transcription factor K-box SRF-TF
AT3G66656.1 AGL91; transcription factor SRF-TF
AT4G02235.1 AGL51; transcription factor SRF-TF
AT4G09960.1 STK (SEEDSTICK); transcription factor K-box SRF-TF
AT4G09960.2 STK (SEEDSTICK); transcription factor K-box SRF-TF
AT4G09960.3 STK (SEEDSTICK) K-box SRF-TF
AT4G11250.1 AGL52; transcription factor SRF-TF
AT4G11880.1 AGL14 (AGAMOUS-LIKE 14); DNA binding / transcription factor K-box SRF-TF
AT4G18960.1 AG (AGAMOUS); transcription factor K-box SRF-TF
AT4G22950.1 AGL19 (AGAMOUS-LIKE 19); transcription factor K-box SRF-TF
AT4G24540.1 AGL24 (AGAMOUS-LIKE 24); protein binding / protein heterodimerization/ protein homodimerization/ transcription factor K-box SRF-TF
AT4G36590.1 MADS-box protein (AGL40) SRF-TF
AT4G37940.1 AGL21 (AGAMOUS-LIKE 21); transcription factor K-box SRF-TF
AT5G04640.1 AGL99; DNA binding / transcription factor SRF-TF
AT5G06500.1 AGL96; DNA binding / transcription factor SRF-TF
AT5G10140.1 FLC (FLOWERING LOCUS C); transcription factor K-box SRF-TF
AT5G10140.2 FLC (FLOWERING LOCUS C) K-box SRF-TF
AT5G13790.1 AGL15 (AGAMOUS-LIKE 15); DNA binding / transcription factor K-box SRF-TF
AT5G15800.1 SEP1 (SEPALLATA1); DNA binding / transcription factor K-box SRF-TF
AT5G15800.2 SEP1 (SEPALLATA1) K-box SRF-TF
AT5G20240.1 PI (PISTILLATA); DNA binding / transcription factor K-box SRF-TF
AT5G23260.1 TT16 (TRANSPARENT TESTA16); transcription factor K-box SRF-TF
AT5G23260.2 TT16 (TRANSPARENT TESTA16); transcription factor K-box SRF-TF
AT5G23260.3 TT16 (TRANSPARENT TESTA16) K-box SRF-TF
AT5G26580.1 AGL34 (AGAMOUS LIKE-34); DNA binding / transcription factor SRF-TF
AT5G26630.1 MADS-box protein (AGL35) SRF-TF
AT5G26650.1 AGL36; DNA binding / transcription factor SRF-TF
AT5G26870.1 AGL26; transcription factor SRF-TF
AT5G26950.1 AGL93; transcription factor SRF-TF
AT5G27050.1 AGL101; transcription factor SRF-TF
AT5G27070.1 AGL53; transcription factor SRF-TF
AT5G27090.1 AGL54; transcription factor SRF-TF
AT5G27090.2 AGL54 SRF-TF
AT5G27130.1 AGL39; DNA binding / transcription factor SRF-TF
AT5G27580.1 AGL89; transcription factor SRF-TF
AT5G27944.1 sequence-specific DNA binding / transcription factor SRF-TF
AT5G27960.1 MADS-box protein (AGL90) SRF-TF
AT5G37415.1 transcription factor SRF-TF
AT5G38620.1 MADS-box protein (AGL73) SRF-TF
AT5G38740.1 AGL77; transcription factor SRF-TF
AT5G39750.1 AGL81/EMB3008 (EMBRYO DEFECTIVE 3008); transcription factor SRF-TF
AT5G39810.1 AGL98; transcription factor SRF-TF
AT5G40120.1 AGL76; DNA binding / transcription factor SRF-TF
AT5G40220.1 AGL43; transcription factor SRF-TF
AT5G41200.1 AGL75; DNA binding / transcription factor SRF-TF
AT5G48670.1 AGL80/FEM111 (AGAMOUS-LIKE80); DNA binding / transcription factor SRF-TF
AT5G49420.1 MADS-box protein (AGL84) SRF-TF
AT5G49490.1 AGL83; DNA binding / transcription factor SRF-TF
AT5G51860.1 MADS-box protein (AGL72) K-box SRF-TF
AT5G51860.2 MADS-box protein (AGL72) K-box SRF-TF
AT5G51870.1 AGL71; transcription factor K-box SRF-TF
AT5G51870.2 AGL71; transcription factor K-box SRF-TF
AT5G55690.1 MADS-box protein (AGL47) SRF-TF
AT5G58890.1 AGL82; DNA binding / transcription factor SRF-TF
AT5G60440.1 MADS-box protein (AGL62) SRF-TF
AT5G60910.1 AGL8 (AGAMOUS-LIKE 8); transcription factor K-box SRF-TF
AT5G62165.1 AGL42 (AGAMOUS LIKE 42); transcription factor K-box SRF-TF
AT5G62165.2 AGL42 (AGAMOUS LIKE 42); transcription factor K-box SRF-TF
AT5G62165.3 AGL42 (AGAMOUS LIKE 42); transcription factor K-box SRF-TF
AT5G65050.1 AGL31 (AGAMOUS LIKE MADS-BOX PROTEIN 31); transcription factor SRF-TF
AT5G65050.2 AGL31 (AGAMOUS LIKE MADS-BOX PROTEIN 31) K-box SRF-TF
AT5G65050.3 AGL31 (AGAMOUS LIKE MADS-BOX PROTEIN 31) K-box SRF-TF
AT5G65060.1 MAF3 (MADS AFFECTING FLOWERING 3); transcription factor K-box SRF-TF
AT5G65060.2 MAF3 (MADS AFFECTING FLOWERING 3); transcription factor K-box SRF-TF
AT5G65070.1 MAF4 (MADS AFFECTING FLOWERING 4); transcription factor K-box SRF-TF
AT5G65070.2 MAF4 (MADS AFFECTING FLOWERING 4) K-box SRF-TF
AT5G65080.1 AGL68/MAF5 (MADS AFFECTING FLOWERING 5); transcription factor K-box SRF-TF
AT5G65080.2 AGL68/MAF5 (MADS AFFECTING FLOWERING 5) K-box SRF-TF
AT5G65330.1 AGL78; transcription factor SRF-TF

General references

Jack, T. 2001. Plant development going MADS. Plant Mol. Biol. 46(5):515-20 PUBMEDID:11516144
Nam, J; dePamphilis, CW; Ma, H; Nei, M. 2003. Antiquity and evolution of the MADS-box gene family controlling flower development in plants. Mol. Biol. Evol. 20(9):1435-47 PUBMEDID:12777513
Nam, J; Kim, J; Lee, S; An, G; Ma, H; Nei, M. 2004. Type I MADS-box genes have experienced faster birth-and-death evolution than type II MADS-box genes in angiosperms. Proc. Natl. Acad. Sci. U.S.A. 101(7):1910-5 PUBMEDID:14764899
Ng, M; Yanofsky, MF. 2001. Function and evolution of the plant MADS-box gene family. Nat. Rev. Genet. 2(3):186-95 PUBMEDID:11256070
Riechmann, JL; Meyerowitz, EM. 1997. MADS domain proteins in plant development. Biol. Chem. 378(10):1079-101 PUBMEDID:9372178
Shore, P; Sharrocks, AD. 1995. The MADS-box family of transcription factors. Eur. J. Biochem. 229(1):1-13 PUBMEDID:7744019
West, AG; Sharrocks, AD. 1999. MADS-box transcription factors adopt alternative mechanisms for bending DNA. J. Mol. Biol. 286(5):1311-23 PUBMEDID:10064699

Specific references

Rounsley, SD; Ditta, GS; Yanofsky, MF. 1995. Diverse roles for MADS box genes in Arabidopsis development. Plant Cell 7(8):1259-69 PUBMEDID:7549482