Plant Transcription factor database - Universität Potsdam
version: 3.0

Arabidopsis thaliana MBF1 Family


Tsuda et al. 2004: Multiprotein bridging factor 1 (MBF1) is known to be a transcriptional co-activator that mediates transcriptional activation by bridging between an activator and a TATA-box binding protein (TBP). We demonstrated that expression of every three MBF1 from Arabidopsis partially rescues the yeast mbf1 mutant phenotype, indicating that all of them function as co-activators for GCN4-dependent transcriptional activation. We also report that each of their subtypes shows distinct tissue-specific expression patterns and responses to phytohormones. These observations suggest that even though they share a similar biochemical function, each MBF1 has distinct roles in various tissues and conditions.

Members of this family
  SHOULD possess MBF1 domain

Domain alignments

This family is also present in:


There are 3 gene models in this family

Gene modelDescriptionDomains
AT2G42680.1 ATMBF1A/MBF1A (MULTIPROTEIN BRIDGING FACTOR 1A); DNA binding / transcription coactivator HTH_3 MBF1
AT3G24500.1 ATMBF1C/MBF1C (MULTIPROTEIN BRIDGING FACTOR 1C); DNA binding / transcription coactivator/ transcription factor HTH_3 MBF1
AT3G58680.1 ATMBF1B/MBF1B (MULTIPROTEIN BRIDGING FACTOR 1B); DNA binding / transcription coactivator HTH_3 MBF1

General references

Tsuda, K; Tsuji, T; Hirose, S; Yamazaki, K. 2004. Three Arabidopsis MBF1 homologs with distinct expression profiles play roles as transcriptional co-activators. Plant Cell Physiol. 45(2):225-31 PUBMEDID:14988493

Specific references

Sugikawa, Y; Ebihara, S; Tsuda, K; Niwa, Y; Yamazaki, K. 2005. Transcriptional coactivator MBF1s from Arabidopsis predominantly localize in nucleolus. J. Plant Res. 118(6):431-7 PUBMEDID:16283071