Plant Transcription factor database - Universität Potsdam
version: 3.0

Micromonas sp. RCC299 MYB Family

Description

Martin & Paz-Ares. 1997: The cloning of the first transcription factor from plants, the C1 gene of maize, indicated that plants use transcription factors that are structurally related to those of animals in their control of gene expression, because C1 showed significant structural homology to the vertebrate cellular proto-oncogene c-MYB. Since 1987, the catalogue of MYB-related transcription factors has increased considerably in size due, primarily, to the ever-expanding number of MYB genes identified in higher plants (Arabidopsis thaliana is estimated to contain more than a hundred MYB genes). In vertebrates, the MYB-related proto-oncogenes comprise a small family with a central role in controlling cellular proliferation and commitment to development. However, while the functions of some plant MYB genes are relatively well understood they are, at present, quite distinct from their animal counterparts.

Members of this family
  SHOULD possess Myb_DNA-binding domain
  SHOULD NOT possess ARID Response_reg SNF2_N domains

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for the families MYB and MYB-related jointly. The data reported by Yanhui et al. 2006 for A. thaliana were taken as gold standard.

The gold standard reported 198 members for this families, 184 of which are present in ArabTFDB, giving a PPV of 0.88. Fourteen additional members not present in ArabTFDB might be false negatives, giving a Sensitivity of 0.93.

This family is also present in:

References

There are 14 gene models in this family



Gene modelDescriptionDomains
103168 fgenesh2_pg.C_Chr_11000280 Myb_DNA-binding
105509 estExt_fgenesh2_pg.C_Chr_040472 Myb_DNA-binding
108200 est_cluster_kg.Chr_05__9__3201847:1 Myb_DNA-binding
109612 est_cluster_kg.Chr_16__9__3199970:1 Myb_DNA-binding
113455 MSI_PierreAnnot2.00118 Myb_DNA-binding
61072 EuGene.0900010055 Myb_DNA-binding zf-CCHC
73264 gw2.05.651.1 Myb_DNA-binding
73784 gw2.15.275.1 Myb_DNA-binding
74639 gw2.16.261.1 Myb_DNA-binding
74650 gw2.02.861.1 Myb_DNA-binding
77618 e_gw2.01.888.1 Myb_DNA-binding
83790 e_gw2.07.474.1 Myb_DNA-binding
88104 e_gw2.14.322.1 Myb_DNA-binding
92928 estExt_Genewise2Plus.C_Chr_010477 Myb_DNA-binding

General references

Jin, H; Martin, C. 1999. Multifunctionality and diversity within the plant MYB-gene family. Plant Mol. Biol. 41(5):577-85 PUBMEDID:10645718
Klempnauer, KH; Sippel, AE. 1987. The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain. EMBO J. 6(9):2719-25 PUBMEDID:2824190
Martin, C; Paz-Ares, J. 1997. MYB transcription factors in plants. Trends Genet. 13(2):67-73 PUBMEDID:9055608