Plant Transcription factor database - Universität Potsdam
version: 3.0

Selaginella moellendorffii MYB Family

Description

Martin & Paz-Ares. 1997: The cloning of the first transcription factor from plants, the C1 gene of maize, indicated that plants use transcription factors that are structurally related to those of animals in their control of gene expression, because C1 showed significant structural homology to the vertebrate cellular proto-oncogene c-MYB. Since 1987, the catalogue of MYB-related transcription factors has increased considerably in size due, primarily, to the ever-expanding number of MYB genes identified in higher plants (Arabidopsis thaliana is estimated to contain more than a hundred MYB genes). In vertebrates, the MYB-related proto-oncogenes comprise a small family with a central role in controlling cellular proliferation and commitment to development. However, while the functions of some plant MYB genes are relatively well understood they are, at present, quite distinct from their animal counterparts.

Members of this family
  SHOULD possess Myb_DNA-binding domain
  SHOULD NOT possess ARID Response_reg SNF2_N domains

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for the families MYB and MYB-related jointly. The data reported by Yanhui et al. 2006 for A. thaliana were taken as gold standard.

The gold standard reported 198 members for this families, 184 of which are present in ArabTFDB, giving a PPV of 0.88. Fourteen additional members not present in ArabTFDB might be false negatives, giving a Sensitivity of 0.93.

This family is also present in:

References

There are 22 gene models in this family



Gene modelDescriptionDomains
100734 e_gw1.23.519.1 Myb_DNA-binding
109587 e_gw1.38.250.1 Myb_DNA-binding
113921 e_gw1.47.324.1 Myb_DNA-binding
140962 estExt_Genewise1.C_11907 Myb_DNA-binding
179572 estExt_Genewise1Plus.C_540165 Myb_DNA-binding
233652 fgenesh1_pm.C_scaffold_47000022 Myb_DNA-binding
29437 gw1.0.1018.1 Myb_DNA-binding
38644 gw1.23.520.1 Myb_DNA-binding
437219 estExt_fgenesh2_pg.C_00034 Myb_DNA-binding
47768 gw1.100.218.1 Myb_DNA-binding
59725 gw1.55.500.1 Myb_DNA-binding
6091 gw1.39.40.1 Myb_DNA-binding
6282 gw1.35.79.1 Myb_DNA-binding
72632 gw1.0.2774.1 Myb_DNA-binding
75978 e_gw1.1.964.1 Myb_DNA-binding
77255 e_gw1.1.1981.1 Myb_DNA-binding
80553 e_gw1.3.109.1 Myb_DNA-binding
81112 e_gw1.4.838.1 Myb_DNA-binding
81360 e_gw1.4.125.1 Myb_DNA-binding
84369 e_gw1.6.739.1 Myb_DNA-binding
98669 e_gw1.20.478.1 Myb_DNA-binding
99462 e_gw1.22.133.1 Myb_DNA-binding

General references

Jin, H; Martin, C. 1999. Multifunctionality and diversity within the plant MYB-gene family. Plant Mol. Biol. 41(5):577-85 PUBMEDID:10645718
Klempnauer, KH; Sippel, AE. 1987. The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain. EMBO J. 6(9):2719-25 PUBMEDID:2824190
Martin, C; Paz-Ares, J. 1997. MYB transcription factors in plants. Trends Genet. 13(2):67-73 PUBMEDID:9055608