Plant Transcription factor database - Universität Potsdam
version: 3.0

Cyanidioschyzon merolae MYB-related Family


Martin & Paz-Ares. 1997: The cloning of the first transcription factor from plants, the C1 gene of maize, indicated that plants use transcription factors that are structurally related to those of animals in their control of gene expression, because C1 showed significant structural homology to the vertebrate cellular proto-oncogene c-MYB. Since 1987, the catalogue of MYB-related transcription factors has increased considerably in size due, primarily, to the ever-expanding number of MYB genes identified in higher plants (Arabidopsis thaliana is estimated to contain more than a hundred MYB genes). In vertebrates, the MYB-related proto-oncogenes comprise a small family with a central role in controlling cellular proliferation and commitment to development. However, while the functions of some plant MYB genes are relatively well understood they are, at present, quite distinct from their animal counterparts.

Members of this family
  SHOULD possess Myb_DNA-binding domain
  SHOULD NOT possess ARID G2-like Response_reg SNF2_N trihelix domains

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for the families MYB and MYB-related jointly. The data reported by Yanhui et al. 2006 for A. thaliana were taken as gold standard.

The gold standard reported 198 members for this families, 184 of which are present in ArabTFDB, giving a PPV of 0.88. Fourteen additional members not present in ArabTFDB might be false negatives, giving a Sensitivity of 0.93.

This family is also present in:


There are 21 gene models in this family

Gene modelDescriptionDomains
CMA023C MYB-related protein Myb_DNA-binding
CMB159C MYB-related protein Myb_DNA-binding
CMD181C similar to RNA polymerase III transcription factor IIIB chain B'' Myb_DNA-binding
CME134C hypothetical protein Myb_DNA-binding
CME142C similar to retinoblastoma binding protein 2 Myb_DNA-binding PHD
CMK043C MYB-related protein Myb_DNA-binding
CML061C SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c Myb_DNA-binding SWIRM ZZ
CML101C MYB-related protein Myb_DNA-binding
CML246C MYB-related protein Myb_DNA-binding
CMM233C SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c Myb_DNA-binding SWIRM ZZ
CMN257C similar to DNMT1 associated protein 1 Myb_DNA-binding
CMO298C hypothetical protein Myb_DNA-binding
CMO347C MYB-related protein Mov34 Myb_DNA-binding
CMP069C MYB-related protein Myb_DNA-binding
CMP134C similar to transcriptional adaptor like protein Myb_DNA-binding ZZ
CMP232C hypothetical protein Myb_DNA-binding
CMP254C MYB-related protein Myb_DNA-binding
CMR124C MYB-related protein Myb_DNA-binding
CMR337C hypothetical protein Myb_DNA-binding
CMS371C MYB-related protein Myb_DNA-binding
CMT266C MYB-related protein Myb_DNA-binding

General references

Jin, H; Martin, C. 1999. Multifunctionality and diversity within the plant MYB-gene family. Plant Mol. Biol. 41(5):577-85 PUBMEDID:10645718
Klempnauer, KH; Sippel, AE. 1987. The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain. EMBO J. 6(9):2719-25 PUBMEDID:2824190
Martin, C; Paz-Ares, J. 1997. MYB transcription factors in plants. Trends Genet. 13(2):67-73 PUBMEDID:9055608