Plant Transcription factor database - Universität Potsdam
version: 3.0

Chlorella sp. NC64A MYB-related Family

Description

Martin & Paz-Ares. 1997: The cloning of the first transcription factor from plants, the C1 gene of maize, indicated that plants use transcription factors that are structurally related to those of animals in their control of gene expression, because C1 showed significant structural homology to the vertebrate cellular proto-oncogene c-MYB. Since 1987, the catalogue of MYB-related transcription factors has increased considerably in size due, primarily, to the ever-expanding number of MYB genes identified in higher plants (Arabidopsis thaliana is estimated to contain more than a hundred MYB genes). In vertebrates, the MYB-related proto-oncogenes comprise a small family with a central role in controlling cellular proliferation and commitment to development. However, while the functions of some plant MYB genes are relatively well understood they are, at present, quite distinct from their animal counterparts.

Members of this family
  SHOULD possess Myb_DNA-binding domain
  SHOULD NOT possess ARID G2-like Response_reg SNF2_N trihelix domains

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for the families MYB and MYB-related jointly. The data reported by Yanhui et al. 2006 for A. thaliana were taken as gold standard.

The gold standard reported 198 members for this families, 184 of which are present in ArabTFDB, giving a PPV of 0.88. Fourteen additional members not present in ArabTFDB might be false negatives, giving a Sensitivity of 0.93.

This family is also present in:

References

There are 14 gene models in this family



Gene modelDescriptionDomains
134832 IGS.gm_12_00218 Myb_DNA-binding SWIRM
13979 gw1.8.311.1 Myb_DNA-binding
142952 IGS.gm_5_00281 Mov34 Myb_DNA-binding
143110 IGS.gm_5_00439 Myb_DNA-binding
14655 gw1.28.76.1 Myb_DNA-binding
15057 gw1.9.308.1 Myb_DNA-binding
15266 gw1.4.455.1 Myb_DNA-binding
49822 fgenesh3_pg.C_scaffold_2000067 Myb_DNA-binding
54975 fgenesh3_pg.C_scaffold_28000005 Agenet Involucrin Myb_DNA-binding PHD zf-MYND
56501 estExt_fgenesh3_pg.C_10164 Myb_DNA-binding
56603 estExt_fgenesh3_pg.C_10363 Myb_DNA-binding
57787 estExt_fgenesh3_pg.C_90188 Myb_DNA-binding
58166 estExt_fgenesh3_pg.C_130097 Myb_DNA-binding PHD
58999 estExt_fgenesh3_pg.C_240053 LRR_1 Myb_DNA-binding Pkinase Pkinase_Tyr

General references

Jin, H; Martin, C. 1999. Multifunctionality and diversity within the plant MYB-gene family. Plant Mol. Biol. 41(5):577-85 PUBMEDID:10645718
Klempnauer, KH; Sippel, AE. 1987. The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain. EMBO J. 6(9):2719-25 PUBMEDID:2824190
Martin, C; Paz-Ares, J. 1997. MYB transcription factors in plants. Trends Genet. 13(2):67-73 PUBMEDID:9055608