Plant Transcription factor database - Universität Potsdam
version: 3.0

Chlamydomonas reinhardtii MYB-related Family

Description

Martin & Paz-Ares. 1997: The cloning of the first transcription factor from plants, the C1 gene of maize, indicated that plants use transcription factors that are structurally related to those of animals in their control of gene expression, because C1 showed significant structural homology to the vertebrate cellular proto-oncogene c-MYB. Since 1987, the catalogue of MYB-related transcription factors has increased considerably in size due, primarily, to the ever-expanding number of MYB genes identified in higher plants (Arabidopsis thaliana is estimated to contain more than a hundred MYB genes). In vertebrates, the MYB-related proto-oncogenes comprise a small family with a central role in controlling cellular proliferation and commitment to development. However, while the functions of some plant MYB genes are relatively well understood they are, at present, quite distinct from their animal counterparts.

Members of this family
  SHOULD possess Myb_DNA-binding domain
  SHOULD NOT possess ARID G2-like Response_reg SNF2_N trihelix domains

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for the families MYB and MYB-related jointly. The data reported by Yanhui et al. 2006 for A. thaliana were taken as gold standard.

The gold standard reported 198 members for this families, 184 of which are present in ArabTFDB, giving a PPV of 0.88. Fourteen additional members not present in ArabTFDB might be false negatives, giving a Sensitivity of 0.93.

This family is also present in:

References

There are 17 gene models in this family



Gene modelDescriptionDomains
116658 e_gwW.1.472.1 Myb_DNA-binding
119194 e_gwW.27.138.1 Myb_DNA-binding
119283 e_gwW.27.121.1 Myb_DNA-binding
119948 e_gwW.31.249.1 Myb_DNA-binding
149109 Chlre2_kg.scaffold_28000057 Myb_DNA-binding
178083 fgenesh2_pg.C_scaffold_46000087 DnaJ Myb_DNA-binding
205561 OVA_estExt_fgenesh2_kg.C_230055 Myb_DNA-binding
284832 au.g3224_t1 Myb_DNA-binding
290570 au.g8585_t1 Myb_DNA-binding SWIRM
298349 kg.chromosome_1_#_74_#_NP1118008 DnaJ Myb_DNA-binding
338485 pm.chromosome_10_#_164 Myb_DNA-binding
342954 estExt_fgenesh1_pg.C_chromosome_20554 Myb_DNA-binding
400190 pasa_Sanger_mRNA33565 Myb_DNA-binding
402780 pasa_Sanger_mRNA26573 Myb_DNA-binding
415966 pasa_Sanger_mRNA19529 Myb_DNA-binding
417388 pasa_Sanger_mRNA22699 Myb_DNA-binding
426728 pasa_Sanger_mRNA8862 Myb_DNA-binding

General references

Jin, H; Martin, C. 1999. Multifunctionality and diversity within the plant MYB-gene family. Plant Mol. Biol. 41(5):577-85 PUBMEDID:10645718
Klempnauer, KH; Sippel, AE. 1987. The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain. EMBO J. 6(9):2719-25 PUBMEDID:2824190
Martin, C; Paz-Ares, J. 1997. MYB transcription factors in plants. Trends Genet. 13(2):67-73 PUBMEDID:9055608