Plant Transcription factor database - Universität Potsdam
version: 3.0

Coccomyxa sp. C-169 MYB-related Family

Description

Martin & Paz-Ares. 1997: The cloning of the first transcription factor from plants, the C1 gene of maize, indicated that plants use transcription factors that are structurally related to those of animals in their control of gene expression, because C1 showed significant structural homology to the vertebrate cellular proto-oncogene c-MYB. Since 1987, the catalogue of MYB-related transcription factors has increased considerably in size due, primarily, to the ever-expanding number of MYB genes identified in higher plants (Arabidopsis thaliana is estimated to contain more than a hundred MYB genes). In vertebrates, the MYB-related proto-oncogenes comprise a small family with a central role in controlling cellular proliferation and commitment to development. However, while the functions of some plant MYB genes are relatively well understood they are, at present, quite distinct from their animal counterparts.

Members of this family
  SHOULD possess Myb_DNA-binding domain
  SHOULD NOT possess ARID G2-like Response_reg SNF2_N trihelix domains

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for the families MYB and MYB-related jointly. The data reported by Yanhui et al. 2006 for A. thaliana were taken as gold standard.

The gold standard reported 198 members for this families, 184 of which are present in ArabTFDB, giving a PPV of 0.88. Fourteen additional members not present in ArabTFDB might be false negatives, giving a Sensitivity of 0.93.

This family is also present in:

References

There are 14 gene models in this family



Gene modelDescriptionDomains
101734 igs.C169-scaffold_13-gm_43 Myb_DNA-binding
15201 gw1.9.85.1 Myb_DNA-binding ZZ
22635 gw1.4.802.1 Myb_DNA-binding
60596 GG.C169_S06_00409 Myb_DNA-binding
70518 fgeneshCV_pg.C_scaffold_1000277 Myb_DNA-binding
70912 fgeneshCV_pg.C_scaffold_2000049 Myb_DNA-binding
71086 fgeneshCV_pg.C_scaffold_2000223 Myb_DNA-binding
71102 fgeneshCV_pg.C_scaffold_2000239 Myb_DNA-binding
72180 fgeneshCV_pg.C_scaffold_4000282 Myb_DNA-binding
72270 fgeneshCV_pg.C_scaffold_4000372 Myb_DNA-binding RRM_1 zf-RanBP
73598 fgeneshCV_pg.C_scaffold_7000363 Myb_DNA-binding
82099 estExt_fgeneshCV_pg.C_40436 Myb_DNA-binding
82397 estExt_fgeneshCV_pg.C_60079 Myb_DNA-binding
82454 estExt_fgeneshCV_pg.C_60178 DnaJ Myb_DNA-binding

General references

Jin, H; Martin, C. 1999. Multifunctionality and diversity within the plant MYB-gene family. Plant Mol. Biol. 41(5):577-85 PUBMEDID:10645718
Klempnauer, KH; Sippel, AE. 1987. The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain. EMBO J. 6(9):2719-25 PUBMEDID:2824190
Martin, C; Paz-Ares, J. 1997. MYB transcription factors in plants. Trends Genet. 13(2):67-73 PUBMEDID:9055608