Plant Transcription factor database - Universität Potsdam
version: 3.0

Galdieria sulphuraria MYB-related Family

Description

Martin & Paz-Ares. 1997: The cloning of the first transcription factor from plants, the C1 gene of maize, indicated that plants use transcription factors that are structurally related to those of animals in their control of gene expression, because C1 showed significant structural homology to the vertebrate cellular proto-oncogene c-MYB. Since 1987, the catalogue of MYB-related transcription factors has increased considerably in size due, primarily, to the ever-expanding number of MYB genes identified in higher plants (Arabidopsis thaliana is estimated to contain more than a hundred MYB genes). In vertebrates, the MYB-related proto-oncogenes comprise a small family with a central role in controlling cellular proliferation and commitment to development. However, while the functions of some plant MYB genes are relatively well understood they are, at present, quite distinct from their animal counterparts.

Members of this family
  SHOULD possess Myb_DNA-binding domain
  SHOULD NOT possess ARID G2-like Response_reg SNF2_N trihelix domains

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for the families MYB and MYB-related jointly. The data reported by Yanhui et al. 2006 for A. thaliana were taken as gold standard.

The gold standard reported 198 members for this families, 184 of which are present in ArabTFDB, giving a PPV of 0.88. Fourteen additional members not present in ArabTFDB might be false negatives, giving a Sensitivity of 0.93.

This family is also present in:

References

There are 22 gene models in this family



Gene modelDescriptionDomains
Gs00910.1 ref|XP_001637205.1|__predicted protein [Nematostella vectensis] gb|EDO45142.1| predicted protein [Nematostella vectensis] | Symbols: | myb family transcription factor | chr2:19386109-19389274 FORWARD 8758|protein DNA methyltransferase 1-associated protein Myb_DNA-binding
Gs03640.1 ref|XP_636387.1|__myb domain-containing protein [Dictyostelium discoideum AX4] gb|EAL62883.1| myb domain-containing protein [Dictyostelium discoideum AX4] Myb_DNA-binding SSXT
Gs06660.1 ref|XP_636387.1|__myb domain-containing protein [Dictyostelium discoideum AX4] gb|EAL62883.1| myb domain-containing protein [Dictyostelium discoideum AX4] Myb_DNA-binding
Gs07930.1 ref|XP_001482356.1|__hypothetical protein PGUG_05376 [Pichia guilliermondii ATCC 6260] gb|EDK41278.1| hypothetical protein PGUG_05376 [Pichia guilliermondii ATCC 6260] FAD_binding_6 Myb_DNA-binding NAD_binding_1
Gs09320.1 ref|XP_636387.1|__myb domain-containing protein [Dictyostelium discoideum AX4] gb|EAL62883.1| myb domain-containing protein [Dictyostelium discoideum AX4] Myb_DNA-binding
Gs12450.1 ref|XP_640380.1|__myb domain-containing protein [Dictyostelium discoideum AX4] gb|EAL66406.1| myb domain-containing protein [Dictyostelium discoideum AX4] Myb_DNA-binding
Gs13360.1 dbj|BAD92243.1|__SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2 isoform b variant [Homo sapiens] | Symbols: CHB4, ATSWI3C | ATSWI3C (Arabidopsis thaliana switching protein 3C) Myb_DNA-binding SWIRM ZZ
Gs18610.1 ref|XP_636387.1|__myb domain-containing protein [Dictyostelium discoideum AX4] gb|EAL62883.1| myb domain-containing protein [Dictyostelium discoideum AX4] Myb_DNA-binding
Gs23720.1 ref|XP_636387.1|__myb domain-containing protein [Dictyostelium discoideum AX4] gb|EAL62883.1| myb domain-containing protein [Dictyostelium discoideum AX4] Myb_DNA-binding
Gs24430.1 ref|XP_636387.1|__myb domain-containing protein [Dictyostelium discoideum AX4] gb|EAL62883.1| myb domain-containing protein [Dictyostelium discoideum AX4] Myb_DNA-binding
Gs36470.1 Myb_DNA-binding
Gs39290.1 ref|XP_001444559.1|__hypothetical protein [Paramecium tetraurelia] emb|CAK77162.1| unnamed protein product [Paramecium tetraurelia] Myb_DNA-binding ZZ
Gs41350.1 ref|XP_644160.1|__myb domain-containing protein [Dictyostelium discoideum AX4] gb|AAO52494.1| similar to Dictyostelium discoideum (Slime mold). Protein kinase YakA gb|EAL70124.1| myb domain-containing protein [Dictyostelium discoideum AX4] | Symbols: | my Myb_DNA-binding
Gs43200.1 ref|NP_001056559.1|__Os06g0105800 [Oryza sativa (japonica cultivar-group)] dbj|BAD67706.1| putative MYB29 protein [Oryza sativa (japonica cultivar-group)] dbj|BAF18473.1| Os06g0105800 [Oryza sativa (japonica cultivar-group)] Myb_DNA-binding
Gs44890.1 ref|XP_001415952.1|__predicted protein [Ostreococcus lucimarinus CCE9901] gb|ABO94244.1| predicted protein [Ostreococcus lucimarinus CCE9901] | Symbols: | DNA binding / transcription factor | chr4:18236822-18239738 FORWARD Myb_DNA-binding
Gs46180.1 ref|XP_644160.1|__myb domain-containing protein [Dictyostelium discoideum AX4] gb|AAO52494.1| similar to Dictyostelium discoideum (Slime mold). Protein kinase YakA gb|EAL70124.1| myb domain-containing protein [Dictyostelium discoideum AX4] | Symbols: | my Myb_DNA-binding
Gs47810.1 emb|CAO39639.1|__unnamed protein product [Vitis vinifera] Myb_DNA-binding
Gs53140.1 ref|XP_636387.1|__myb domain-containing protein [Dictyostelium discoideum AX4] gb|EAL62883.1| myb domain-containing protein [Dictyostelium discoideum AX4] Myb_DNA-binding
Gs55140.1 ref|XP_001422948.1|__predicted protein [Ostreococcus lucimarinus CCE9901] gb|ABP01307.1| predicted protein [Ostreococcus lucimarinus CCE9901] Myb_DNA-binding ZZ
Gs56510.1 ref|XP_636387.1|__myb domain-containing protein [Dictyostelium discoideum AX4] gb|EAL62883.1| myb domain-containing protein [Dictyostelium discoideum AX4] Myb_DNA-binding
Gs59450.1 ref|XP_636387.1|__myb domain-containing protein [Dictyostelium discoideum AX4] gb|EAL62883.1| myb domain-containing protein [Dictyostelium discoideum AX4] Myb_DNA-binding
Gs63230.1 ref|XP_636518.1|__myb domain-containing protein [Dictyostelium discoideum AX4] gb|EAL63013.1| myb domain-containing protein [Dictyostelium discoideum AX4] Myb_DNA-binding

General references

Jin, H; Martin, C. 1999. Multifunctionality and diversity within the plant MYB-gene family. Plant Mol. Biol. 41(5):577-85 PUBMEDID:10645718
Klempnauer, KH; Sippel, AE. 1987. The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain. EMBO J. 6(9):2719-25 PUBMEDID:2824190
Martin, C; Paz-Ares, J. 1997. MYB transcription factors in plants. Trends Genet. 13(2):67-73 PUBMEDID:9055608