Plant Transcription factor database - Universität Potsdam
version: 3.0

Micromonas sp. RCC299 MYB-related Family

Description

Martin & Paz-Ares. 1997: The cloning of the first transcription factor from plants, the C1 gene of maize, indicated that plants use transcription factors that are structurally related to those of animals in their control of gene expression, because C1 showed significant structural homology to the vertebrate cellular proto-oncogene c-MYB. Since 1987, the catalogue of MYB-related transcription factors has increased considerably in size due, primarily, to the ever-expanding number of MYB genes identified in higher plants (Arabidopsis thaliana is estimated to contain more than a hundred MYB genes). In vertebrates, the MYB-related proto-oncogenes comprise a small family with a central role in controlling cellular proliferation and commitment to development. However, while the functions of some plant MYB genes are relatively well understood they are, at present, quite distinct from their animal counterparts.

Members of this family
  SHOULD possess Myb_DNA-binding domain
  SHOULD NOT possess ARID G2-like Response_reg SNF2_N trihelix domains

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for the families MYB and MYB-related jointly. The data reported by Yanhui et al. 2006 for A. thaliana were taken as gold standard.

The gold standard reported 198 members for this families, 184 of which are present in ArabTFDB, giving a PPV of 0.88. Fourteen additional members not present in ArabTFDB might be false negatives, giving a Sensitivity of 0.93.

This family is also present in:

References

There are 18 gene models in this family



Gene modelDescriptionDomains
104814 estExt_fgenesh2_kg.C_Chr_050003 Myb_DNA-binding SWIRM
105273 estExt_fgenesh2_pg.C_Chr_030243 AT_hook Myb_DNA-binding
105391 estExt_fgenesh2_pg.C_Chr_040069 Myb_DNA-binding
105915 estExt_fgenesh2_pg.C_Chr_080053 Myb_DNA-binding
106147 estExt_fgenesh2_pg.C_Chr_100176 Myb_DNA-binding
106228 estExt_fgenesh2_pg.C_Chr_110083 Myb_DNA-binding
112657 SAR_estExt_fgenesh2_kg.C_Chr_050003 Myb_DNA-binding SWIRM
113469 AZW_PierreAnnot2.00051 Myb_DNA-binding
113932 MSI_PierreAnnot2.00057 Myb_DNA-binding
56741 EuGene.0300010169 Myb_DNA-binding
57866 EuGene.0400010395 Myb_DNA-binding
58347 EuGene.0500010080 Myb_DNA-binding
61442 EuGene.0900010425 Myb_DNA-binding
62804 EuGene.1100010590 ABC_tran Myb_DNA-binding
63313 EuGene.1200010485 AT_hook Myb_DNA-binding
63353 EuGene.1300010003 Mov34 Myb_DNA-binding
80246 e_gw2.03.717.1 Myb_DNA-binding
82818 e_gw2.06.176.1 Myb_DNA-binding SWIRM ZZ

General references

Jin, H; Martin, C. 1999. Multifunctionality and diversity within the plant MYB-gene family. Plant Mol. Biol. 41(5):577-85 PUBMEDID:10645718
Klempnauer, KH; Sippel, AE. 1987. The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain. EMBO J. 6(9):2719-25 PUBMEDID:2824190
Martin, C; Paz-Ares, J. 1997. MYB transcription factors in plants. Trends Genet. 13(2):67-73 PUBMEDID:9055608