Plant Transcription factor database - Universität Potsdam
version: 3.0

Ostreococcus lucimarinus MYB-related Family

Description

Martin & Paz-Ares. 1997: The cloning of the first transcription factor from plants, the C1 gene of maize, indicated that plants use transcription factors that are structurally related to those of animals in their control of gene expression, because C1 showed significant structural homology to the vertebrate cellular proto-oncogene c-MYB. Since 1987, the catalogue of MYB-related transcription factors has increased considerably in size due, primarily, to the ever-expanding number of MYB genes identified in higher plants (Arabidopsis thaliana is estimated to contain more than a hundred MYB genes). In vertebrates, the MYB-related proto-oncogenes comprise a small family with a central role in controlling cellular proliferation and commitment to development. However, while the functions of some plant MYB genes are relatively well understood they are, at present, quite distinct from their animal counterparts.

Members of this family
  SHOULD possess Myb_DNA-binding domain
  SHOULD NOT possess ARID G2-like Response_reg SNF2_N trihelix domains

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for the families MYB and MYB-related jointly. The data reported by Yanhui et al. 2006 for A. thaliana were taken as gold standard.

The gold standard reported 198 members for this families, 184 of which are present in ArabTFDB, giving a PPV of 0.88. Fourteen additional members not present in ArabTFDB might be false negatives, giving a Sensitivity of 0.93.

This family is also present in:

References

There are 16 gene models in this family



Gene modelDescriptionDomains
13931 fgenesh1_pg.C_Chr_1000391 Myb_DNA-binding
17449 fgenesh1_pg.C_Chr_11000251 Myb_DNA-binding
23972 estExt_fgenesh1_pg.C_Chr_10464 Myb_DNA-binding
27049 eugene.1300010071 Myb_DNA-binding
2829 gwEuk.21.94.1 Myb_DNA-binding ZZ
30413 eugene.0300010089 Myb_DNA-binding
30541 eugene.0300010217 Myb_DNA-binding
32661 eugene.0700010258 Myb_DNA-binding
51202 estExt_Genewise_ext.C_Chr_130129 Myb_DNA-binding SWIRM ZZ
5960 gwEuk.6.396.1 Myb_DNA-binding
6612 gwEuk.4.447.1 Myb_DNA-binding
8087 gwEuk.3.624.1 Myb_DNA-binding
9264 gwEuk.18.58.1 Myb_DNA-binding
93535 ost_12_007_088 Myb_DNA-binding
9418 gwEuk.6.620.1 Myb_DNA-binding
9737 gwEuk.5.591.1 Myb_DNA-binding

General references

Jin, H; Martin, C. 1999. Multifunctionality and diversity within the plant MYB-gene family. Plant Mol. Biol. 41(5):577-85 PUBMEDID:10645718
Klempnauer, KH; Sippel, AE. 1987. The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain. EMBO J. 6(9):2719-25 PUBMEDID:2824190
Martin, C; Paz-Ares, J. 1997. MYB transcription factors in plants. Trends Genet. 13(2):67-73 PUBMEDID:9055608