Plant Transcription factor database - Universität Potsdam
version: 3.0

Ostreococcus tauri MYB-related Family

Description

Martin & Paz-Ares. 1997: The cloning of the first transcription factor from plants, the C1 gene of maize, indicated that plants use transcription factors that are structurally related to those of animals in their control of gene expression, because C1 showed significant structural homology to the vertebrate cellular proto-oncogene c-MYB. Since 1987, the catalogue of MYB-related transcription factors has increased considerably in size due, primarily, to the ever-expanding number of MYB genes identified in higher plants (Arabidopsis thaliana is estimated to contain more than a hundred MYB genes). In vertebrates, the MYB-related proto-oncogenes comprise a small family with a central role in controlling cellular proliferation and commitment to development. However, while the functions of some plant MYB genes are relatively well understood they are, at present, quite distinct from their animal counterparts.

Members of this family
  SHOULD possess Myb_DNA-binding domain
  SHOULD NOT possess ARID G2-like Response_reg SNF2_N trihelix domains

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for the families MYB and MYB-related jointly. The data reported by Yanhui et al. 2006 for A. thaliana were taken as gold standard.

The gold standard reported 198 members for this families, 184 of which are present in ArabTFDB, giving a PPV of 0.88. Fourteen additional members not present in ArabTFDB might be false negatives, giving a Sensitivity of 0.93.

This family is also present in:

References

There are 16 gene models in this family



Gene modelDescriptionDomains
10207 fgenesh1_pg.C_Chr_03.0001000152 Myb_DNA-binding
13789 fgenesh1_pg.C_Chr_15.0001000108 Myb_DNA-binding
16627 e_gw1.04.00.501.1 Myb_DNA-binding
17636 e_gw1.06.00.251.1 Myb_DNA-binding
20688 e_gw1.13.00.112.1 Myb_DNA-binding SWIRM ZZ
23226 estExt_fgenesh1_pg.C_Chr_01.00010348 Myb_DNA-binding
23435 estExt_fgenesh1_pg.C_Chr_03.00010061 Myb_DNA-binding
24275 estExt_fgenesh1_pg.C_Chr_11.00010228 Myb_DNA-binding
24367 estExt_fgenesh1_pg.C_Chr_13.00010057 Myb_DNA-binding
25878 estExt_genewise1.C_Chr_06.00010302 Myb_DNA-binding
30605 0100010593 Myb_DNA-binding
31084 0200010415 AT_hook Myb_DNA-binding PHD
31406 0200010737 Myb_DNA-binding
33285 0600010132 Myb_DNA-binding
36057 1300010029 DSBA Myb_DNA-binding SWIRM ZZ
37809 1800010213 Myb_DNA-binding

General references

Jin, H; Martin, C. 1999. Multifunctionality and diversity within the plant MYB-gene family. Plant Mol. Biol. 41(5):577-85 PUBMEDID:10645718
Klempnauer, KH; Sippel, AE. 1987. The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain. EMBO J. 6(9):2719-25 PUBMEDID:2824190
Martin, C; Paz-Ares, J. 1997. MYB transcription factors in plants. Trends Genet. 13(2):67-73 PUBMEDID:9055608