Plant Transcription factor database - Universität Potsdam
version: 3.0

Physcomitrella patens MYB-related Family


Martin & Paz-Ares. 1997: The cloning of the first transcription factor from plants, the C1 gene of maize, indicated that plants use transcription factors that are structurally related to those of animals in their control of gene expression, because C1 showed significant structural homology to the vertebrate cellular proto-oncogene c-MYB. Since 1987, the catalogue of MYB-related transcription factors has increased considerably in size due, primarily, to the ever-expanding number of MYB genes identified in higher plants (Arabidopsis thaliana is estimated to contain more than a hundred MYB genes). In vertebrates, the MYB-related proto-oncogenes comprise a small family with a central role in controlling cellular proliferation and commitment to development. However, while the functions of some plant MYB genes are relatively well understood they are, at present, quite distinct from their animal counterparts.

Members of this family
  SHOULD possess Myb_DNA-binding domain
  SHOULD NOT possess ARID G2-like Response_reg SNF2_N trihelix domains

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for the families MYB and MYB-related jointly. The data reported by Yanhui et al. 2006 for A. thaliana were taken as gold standard.

The gold standard reported 198 members for this families, 184 of which are present in ArabTFDB, giving a PPV of 0.88. Fourteen additional members not present in ArabTFDB might be false negatives, giving a Sensitivity of 0.93.

This family is also present in:


There are 46 gene models in this family

Gene modelDescriptionDomains
111064 e_gw1.1.456.1 Myb_DNA-binding
111650 e_gw1.2.476.1 Myb_DNA-binding
116913 e_gw1.18.138.1 Myb_DNA-binding SWIRM ZZ
119332 e_gw1.28.319.1 Myb_DNA-binding
131614 e_gw1.89.66.1 Myb_DNA-binding
131940 e_gw1.91.167.1 Myb_DNA-binding
132382 e_gw1.96.88.1 Myb_DNA-binding
138897 e_gw1.151.39.1 Myb_DNA-binding
140225 e_gw1.164.62.1 Myb_DNA-binding
143832 e_gw1.208.13.1 Myb_DNA-binding
143997 e_gw1.210.56.1 Myb_DNA-binding
146252 e_gw1.241.52.1 Myb_DNA-binding
153206 e_gw1.389.24.1 Myb_DNA-binding
160146 estExt_fgenesh1_pg.C_190051 Myb_DNA-binding
161252 estExt_fgenesh1_pg.C_310069 DIRP Myb_DNA-binding
162465 estExt_fgenesh1_pg.C_430108 Myb_DNA-binding
163618 estExt_fgenesh1_pg.C_580112 Myb_DNA-binding SWIRM
168075 estExt_fgenesh1_pg.C_1650042 Myb_DNA-binding
168779 estExt_fgenesh1_pg.C_1880060 Myb_DNA-binding
172310 estExt_fgenesh1_pg.C_3410043 Myb_DNA-binding SWIRM ZZ
172818 estExt_fgenesh1_pg.C_3820023 Myb_DNA-binding
172993 estExt_fgenesh1_pg.C_4010011 Myb_DNA-binding
17324 gw1.89.65.1 Myb_DNA-binding
173268 estExt_fgenesh1_pg.C_4320007 Myb_DNA-binding SWIRM ZZ
19531 gw1.98.100.1 Myb_DNA-binding
211784 estExt_Genewise1.C_730082 Myb_DNA-binding
231675 fgenesh2_pg.scaffold_136000088 DIRP Myb_DNA-binding
24905 gw1.46.107.1 Myb_DNA-binding
27706 gw1.1.287.1 Myb_DNA-binding
29858 gw1.471.6.1 Myb_DNA-binding
29859 gw1.208.10.1 Myb_DNA-binding
29861 gw1.176.42.1 Myb_DNA-binding
29864 gw1.226.61.1 Myb_DNA-binding
29972 gw1.966.1.1 Myb_DNA-binding
39594 gw1.74.171.1 Myb_DNA-binding
77599 fgenesh1_pg.scaffold_66000046 Myb_DNA-binding
77601 fgenesh1_pg.scaffold_66000048 Myb_DNA-binding
78294 fgenesh1_pg.scaffold_70000111 Myb_DNA-binding
79653 fgenesh1_pg.scaffold_80000103 Myb_DNA-binding
80556 fgenesh1_pg.scaffold_87000079 Myb_DNA-binding
8491 gw1.176.27.1 Myb_DNA-binding
87648 fgenesh1_pg.scaffold_160000002 Myb_DNA-binding
9003 gw1.325.30.1 Myb_DNA-binding
90560 fgenesh1_pg.scaffold_198000070 Myb_DNA-binding
91783 fgenesh1_pg.scaffold_215000013 Myb_DNA-binding SWIRM ZZ
94391 fgenesh1_pg.scaffold_260000003 Myb_DNA-binding

General references

Jin, H; Martin, C. 1999. Multifunctionality and diversity within the plant MYB-gene family. Plant Mol. Biol. 41(5):577-85 PUBMEDID:10645718
Klempnauer, KH; Sippel, AE. 1987. The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain. EMBO J. 6(9):2719-25 PUBMEDID:2824190
Martin, C; Paz-Ares, J. 1997. MYB transcription factors in plants. Trends Genet. 13(2):67-73 PUBMEDID:9055608