Plant Transcription factor database - Universität Potsdam
version: 3.0

Arabidopsis thaliana NOZZLE Family


Schiefthaler et al. 1999: Sexual reproduction is a salient aspect of plants, and elaborate structures, such as the flowers of angiosperms, have evolved that aid in this process. Within the flower the corresponding sex organs, the anther and the ovule, form the male and female sporangia, the pollen sac and the nucellus, respectively. However, despite their central role for sexual reproduction little is known about the mechanisms that control the establishment of these important structures. Here we present the identification and molecular characterization of the NOZZLE (NZZ) gene in the flowering plant Arabidopsis thaliana. In several nzz mutants the nucellus and the pollen sac fail to form. It indicates that NZZ plays an early and central role in the development of both types of sporangia and that the mechanisms controlling these processes share a crucial factor. In addition, NZZ may have an early function during male and female sporogenesis as well. The evolutionary aspects of these findings are discussed. NZZ encodes a putative protein of unknown function. However, based on sequence analysis we speculate that NZZ is a nuclear protein and possibly a transcription factor.

Members of this family
  SHOULD possess NOZZLE_Angio domain

This family is also present in:


There are 1 gene models in this family

Gene modelDescriptionDomains

General references

Schiefthaler, U; Balasubramanian, S; Sieber, P; Chevalier, D; Wisman, E; Schneitz, K. 1999. Molecular analysis of NOZZLE, a gene involved in pattern formation and early sporogenesis during sex organ development in Arabidopsis thaliana. Proc. Natl. Acad. Sci. U.S.A. 96(20):11664-9 PUBMEDID:10500234
Wilson, ZA; Yang, C. 2004. Plant gametogenesis: conservation and contrasts in development. Reproduction 128(5):483-92 PUBMEDID:15509694

Specific references

Balasubramanian, S; Schneitz, K. 2000. NOZZLE regulates proximal-distal pattern formation, cell proliferation and early sporogenesis during ovule development in Arabidopsis thaliana. Development 127(19):4227-38 PUBMEDID:10976054
Balasubramanian, S; Schneitz, K. 2002. NOZZLE links proximal-distal and adaxial-abaxial pattern formation during ovule development in Arabidopsis thaliana. Development 129(18):4291-300 PUBMEDID:12183381
Sieber, P; Petrascheck, M; Barberis, A; Schneitz, K. 2004. Organ polarity in Arabidopsis. NOZZLE physically interacts with members of the YABBY family. Plant Physiol. 135(4):2172-85 PUBMEDID:15299139