Plant Transcription factor database - Universität Potsdam
version: 3.0

Chlorella sp. NC64A PHD Family


Bienz. 2006: PHD proteins seem to be found universally in the nucleus, and their functions tend to lie in the control of chromatin or transcription. Increasing evidence indicates that PHD fingers bind to specific nuclear protein partners, for which they apparently use their loop 2 surface. Perhaps each PHD finger has its own cognate nuclear ligand, much like RING fingers have their cognate E2 ligases. No doubt the list of specific PHD finger ligands will grow, and the set of these ligands is likely to reveal whether PHD fingers have a common function in the nucleus.

Members of this family
  SHOULD possess PHD domain
  SHOULD NOT possess Alfin-like DDT Homeobox JmjC JmjN Myb_DNA-binding zf-CCCH domains

Domain alignments

This family is also present in:


There are 21 gene models in this family

Gene modelDescriptionDomains
133598 IGS.gm_1_00734 PHD
133835 IGS.gm_10_00126 PHD
134366 IGS.gm_11_00212 PHD
13462 gw1.18.248.1 PHD
13553 gw1.15.195.1 PHD
137229 IGS.gm_184_00001 PHD
138280 IGS.gm_20_00029 PHD
138585 IGS.gm_21_00064 PHD
139139 IGS.gm_23_00130 AAA BAH PHD
142851 IGS.gm_5_00180 PHD
142883 IGS.gm_5_00212 PHD WAC_Acf1_DNA_bd
143249 IGS.gm_5_00578 PHD
15876 gw1.12.480.1 PHD
19495 e_gw1.3.617.1 PHD
20200 e_gw1.4.490.1 PHD
35680 estExt_Genewise1Plus.C_120014 PHD
50422 fgenesh3_pg.C_scaffold_3000295 PHD SNF2_N zf-C3HC4
51983 fgenesh3_pg.C_scaffold_9000008 Helicase_C PHD
52345 fgenesh3_pg.C_scaffold_10000130 PHD zf-MIZ
54503 fgenesh3_pg.C_scaffold_22000121 FYRN MBD PHD
58651 estExt_fgenesh3_pg.C_180148 PHD

General references

Bienz, M. 2006. The PHD finger, a nuclear protein-interaction domain. Trends Biochem. Sci. 31(1):35-40 PUBMEDID:16297627