Plant Transcription factor database - Universität Potsdam
version: 3.0

Coccomyxa sp. C-169 PHD Family


Bienz. 2006: PHD proteins seem to be found universally in the nucleus, and their functions tend to lie in the control of chromatin or transcription. Increasing evidence indicates that PHD fingers bind to specific nuclear protein partners, for which they apparently use their loop 2 surface. Perhaps each PHD finger has its own cognate nuclear ligand, much like RING fingers have their cognate E2 ligases. No doubt the list of specific PHD finger ligands will grow, and the set of these ligands is likely to reveal whether PHD fingers have a common function in the nucleus.

Members of this family
  SHOULD possess PHD domain
  SHOULD NOT possess Alfin-like DDT Homeobox JmjC JmjN Myb_DNA-binding zf-CCCH domains

Domain alignments

This family is also present in:


There are 22 gene models in this family

Gene modelDescriptionDomains
24298 gw1.10.472.1 PHD
26481 e_gw1.3.154.1 PHD SET
27026 e_gw1.4.821.1 PHD
34457 e_gw1.25.98.1 PHD
40531 estExt_Genewise1Plus.C_10704 PHD
57114 GG.C169_S01_00185 PHD
60434 GG.C169_S06_00247 PHD
62432 GG.C169_S11_00191 PHD
65973 GG.C169_S25_00023 AAA BAH PHD
70312 fgeneshCV_pg.C_scaffold_1000071 Fasciclin Helicase_C PHD
70993 fgeneshCV_pg.C_scaffold_2000130 PHD
71020 fgeneshCV_pg.C_scaffold_2000157 PHD
71154 fgeneshCV_pg.C_scaffold_2000291 PHD
71372 fgeneshCV_pg.C_scaffold_2000509 PHD
74150 fgeneshCV_pg.C_scaffold_9000251 MBD PHD
75732 fgeneshCV_pg.C_scaffold_15000140 PHD WAC_Acf1_DNA_bd
80168 estExt_fgeneshCV_kg.C_260014 BAH PHD
80840 estExt_fgeneshCV_pm.C_150015 PHD
83329 estExt_fgeneshCV_pg.C_110186 Helicase_C PHD
83729 estExt_fgeneshCV_pg.C_140053 PHD zf-MIZ
84404 estExt_fgeneshCV_pg.C_200137 ARID PHD
84735 estExt_fgeneshCV_pg.C_260002 PHD

General references

Bienz, M. 2006. The PHD finger, a nuclear protein-interaction domain. Trends Biochem. Sci. 31(1):35-40 PUBMEDID:16297627