Plant Transcription factor database - Universität Potsdam
version: 3.0

Galdieria sulphuraria PHD Family

Description

Bienz. 2006: PHD proteins seem to be found universally in the nucleus, and their functions tend to lie in the control of chromatin or transcription. Increasing evidence indicates that PHD fingers bind to specific nuclear protein partners, for which they apparently use their loop 2 surface. Perhaps each PHD finger has its own cognate nuclear ligand, much like RING fingers have their cognate E2 ligases. No doubt the list of specific PHD finger ligands will grow, and the set of these ligands is likely to reveal whether PHD fingers have a common function in the nucleus.

Members of this family
  SHOULD possess PHD domain
  SHOULD NOT possess Alfin-like DDT Homeobox JmjC JmjN Myb_DNA-binding zf-CCCH domains

Domain alignments

This family is also present in:

References

There are 5 gene models in this family



Gene modelDescriptionDomains
Gs13660.1 ref|XP_001122984.1|__PREDICTED: similar to CTD-binding SR-like protein rA9 [Apis mellifera] | Symbols: | PHD finger family protein | chr4:6708978-6710919 REVERSE PHD zf-C3HC4
Gs13700.1 emb|CAG32209.1|__hypothetical protein [Gallus gallus] 5548|protein inhibitor of growth protein 5, putative, expressed PHD
Gs29130.1 ref|XP_001657329.1|__zinc finger protein [Aedes aegypti] gb|EAT33689.1| zinc finger protein [Aedes aegypti] | Symbols: PRHA | PRHA (PATHOGENESIS RELATED HOMEODOMAIN PROTEIN A) AT_hook INCENP_ARK-bind PHD
Gs30100.1 emb|CAM21272.1|__PHD finger protein 16 [Mus musculus] PHD
Gs62840.1 ref|XP_454801.1|__unnamed protein product [Kluyveromyces lactis] emb|CAG99888.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140] PHD

General references

Bienz, M. 2006. The PHD finger, a nuclear protein-interaction domain. Trends Biochem. Sci. 31(1):35-40 PUBMEDID:16297627