Plant Transcription factor database - Universität Potsdam
version: 3.0

Micromonas pusilla CCMP1545 PHD Family


Bienz. 2006: PHD proteins seem to be found universally in the nucleus, and their functions tend to lie in the control of chromatin or transcription. Increasing evidence indicates that PHD fingers bind to specific nuclear protein partners, for which they apparently use their loop 2 surface. Perhaps each PHD finger has its own cognate nuclear ligand, much like RING fingers have their cognate E2 ligases. No doubt the list of specific PHD finger ligands will grow, and the set of these ligands is likely to reveal whether PHD fingers have a common function in the nucleus.

Members of this family
  SHOULD possess PHD domain
  SHOULD NOT possess Alfin-like DDT Homeobox JmjC JmjN Myb_DNA-binding zf-CCCH domains

Domain alignments

This family is also present in:


There are 22 gene models in this family

Gene modelDescriptionDomains
12158 gw1.9.686.1 PHD
18869 e_gw1.8.531.1 PHD
19037 e_gw1.8.416.1 PHD
19463 e_gw1.8.537.1 PHD
21435 e_gw1.12.50.1 PHD SET
30544 estExt_Genewise1Plus.C_10016 BAH PHD
36249 estExt_Genewise1Plus.C_140006 AAA BAH PHD
39051 fgenesh1_pg.C_scaffold_3000558 PHD zf-C3HC4
48000 estExt_fgenesh1_pg.C_90008 PHD
48922 estExt_fgenesh1_pg.C_150043 ELM2 PHD
51493 EuGene.0000110015 PHD
51562 EuGene.0000110084 PHD
52469 EuGene.0000130026 PHD
55186 EuGene.0000020215 DNA_methylase PHD
55624 EuGene.0000020653 DNA_methylase PHD
56477 EuGene.0000030631 Agenet PHD
57145 EuGene.0000040271 PHD
58129 EuGene.0000050434 PHD
58710 EuGene.0000060219 PHD
62269 est_orfs.3_1252_4270757:1 PHD
63525 est_orfs.9_2508_4270605:1 PHD
67620 est_orfs.4_6603_4274304:3 PHD

General references

Bienz, M. 2006. The PHD finger, a nuclear protein-interaction domain. Trends Biochem. Sci. 31(1):35-40 PUBMEDID:16297627