Plant Transcription factor database - Universität Potsdam
version: 3.0

Ostreococcus tauri PHD Family

Description

Bienz. 2006: PHD proteins seem to be found universally in the nucleus, and their functions tend to lie in the control of chromatin or transcription. Increasing evidence indicates that PHD fingers bind to specific nuclear protein partners, for which they apparently use their loop 2 surface. Perhaps each PHD finger has its own cognate nuclear ligand, much like RING fingers have their cognate E2 ligases. No doubt the list of specific PHD finger ligands will grow, and the set of these ligands is likely to reveal whether PHD fingers have a common function in the nucleus.

Members of this family
  SHOULD possess PHD domain
  SHOULD NOT possess Alfin-like DDT Homeobox JmjC JmjN Myb_DNA-binding zf-CCCH domains

Domain alignments

This family is also present in:

References

There are 10 gene models in this family



Gene modelDescriptionDomains
16045 e_gw1.03.00.467.1 BAH PHD
17014 e_gw1.04.00.73.1 AAA BAH PHD
23747 estExt_fgenesh1_pg.C_Chr_05.00010256 PHD
30238 0100010226 PHD zf-C3HC4
32246 0400010192 PHD
32258 0400010204 PHD
34305 0800010192 PHD
36515 1400010166 PHD
36895 1500010191 PHD zf-C3HC4
37042 1600010030 PHD

General references

Bienz, M. 2006. The PHD finger, a nuclear protein-interaction domain. Trends Biochem. Sci. 31(1):35-40 PUBMEDID:16297627