Plant Transcription factor database - Universität Potsdam
version: 3.0

Physcomitrella patens PHD Family


Bienz. 2006: PHD proteins seem to be found universally in the nucleus, and their functions tend to lie in the control of chromatin or transcription. Increasing evidence indicates that PHD fingers bind to specific nuclear protein partners, for which they apparently use their loop 2 surface. Perhaps each PHD finger has its own cognate nuclear ligand, much like RING fingers have their cognate E2 ligases. No doubt the list of specific PHD finger ligands will grow, and the set of these ligands is likely to reveal whether PHD fingers have a common function in the nucleus.

Members of this family
  SHOULD possess PHD domain
  SHOULD NOT possess Alfin-like DDT Homeobox JmjC JmjN Myb_DNA-binding zf-CCCH domains

Domain alignments

This family is also present in:


There are 47 gene models in this family

Gene modelDescriptionDomains
108696 estExt_fgenesh1_pm.C_3070006 BAH PHD
120666 e_gw1.33.19.1 Chromo DUF1086 DUF1087 Helicase_C PHD ResIII SNF2_N
124089 e_gw1.47.42.1 PHD SNF2_N
130275 e_gw1.81.157.1 PHD SET
131280 e_gw1.88.104.1 PHD
131736 e_gw1.90.29.1 AAA BAH PHD
145070 e_gw1.223.3.1 PHD PWWP SET
145079 e_gw1.223.67.1 Chromo Helicase_C PHD SNF2_N
145844 e_gw1.235.1.1 Chromo DUF1086 DUF1087 Helicase_C PHD ResIII SNF2_N
148091 e_gw1.271.8.1 PHD
149469 e_gw1.298.38.1 BAH PHD
150355 e_gw1.314.9.1 PHD
153027 e_gw1.384.18.1 BAH PHD
159214 estExt_fgenesh1_pg.C_100194 PHD zf-MIZ
159935 estExt_fgenesh1_pg.C_160242 PHD SAP zf-MIZ
161409 estExt_fgenesh1_pg.C_320151 PHD
161576 estExt_fgenesh1_pg.C_340076 PHD SET
162012 estExt_fgenesh1_pg.C_380106 PHD zf-C3HC4
162345 estExt_fgenesh1_pg.C_420051 Acetyltransf_1 PHD
162981 estExt_fgenesh1_pg.C_500013 PHD
163914 estExt_fgenesh1_pg.C_620038 PHD SAP zf-MIZ
165698 estExt_fgenesh1_pg.C_940024 PHD SAP zf-MIZ
168658 estExt_fgenesh1_pg.C_1840024 PHD
168964 estExt_fgenesh1_pg.C_1950008 PHD
171844 estExt_fgenesh1_pg.C_3130031 PHD
172248 estExt_fgenesh1_pg.C_3380019 Chromo Helicase_C PHD SNF2_N
173726 estExt_fgenesh1_pg.C_6330001 PHD
192056 estExt_gwp_gw1.C_1730002 PHD
194183 estExt_gwp_gw1.C_2120101 PHD SET
197069 estExt_gwp_gw1.C_2820011 FYRC FYRN PHD PWWP SET
213413 estExt_Genewise1.C_890047 BAH PHD
224109 estExt_Genewise1.C_2770068 PHD
27586 gw1.11.150.1 PHD
28493 gw1.311.49.1 PHD
47783 gw1.56.180.1 BAH PHD
5249 gw1.458.5.1 PHD
59496 fgenesh1_pm.scaffold_171000004 BAH PHD
63700 fgenesh1_pg.scaffold_1000074 PHD zf-C3HC4
64283 fgenesh1_pg.scaffold_2000160 PHD
79177 fgenesh1_pg.scaffold_77000008 PHD zf-CCHC
81253 fgenesh1_pg.scaffold_93000055 AT_hook PHD
81336 fgenesh1_pg.scaffold_94000033 PHD
8332 gw1.203.26.1 PHD
85828 fgenesh1_pg.scaffold_138000100 PHD
92690 fgenesh1_pg.scaffold_229000019 PHD zf-CCHC
93608 fgenesh1_pg.scaffold_245000035 Chromo Helicase_C PHD SNF2_N
95550 fgenesh1_pg.scaffold_282000028 AT_hook PHD

General references

Bienz, M. 2006. The PHD finger, a nuclear protein-interaction domain. Trends Biochem. Sci. 31(1):35-40 PUBMEDID:16297627