version: 3.0
Sorghum bicolor PHD Family
Description
Bienz. 2006: PHD proteins seem to be found universally in the nucleus, and their functions tend to lie in the control of chromatin or transcription. Increasing evidence indicates that PHD fingers bind to specific nuclear protein partners, for which they apparently use their loop 2 surface. Perhaps each PHD finger has its own cognate nuclear ligand, much like RING fingers have their cognate E2 ligases. No doubt the list of specific PHD finger ligands will grow, and the set of these ligands is likely to reveal whether PHD fingers have a common function in the nucleus.
Members of this familySHOULD possess PHD domain
SHOULD NOT possess Alfin-like DDT Homeobox JmjC JmjN Myb_DNA-binding zf-CCCH domains
This family is also present in:
- Cyanidioschyzon merolae
- Galdieria sulphuraria
- Micromonas pusilla CCMP1545
- Micromonas sp. RCC299
- Ostreococcus lucimarinus
- Ostreococcus tauri
- Chlamydomonas reinhardtii
- Chlorella sp. NC64A
- Coccomyxa sp. C-169
- Physcomitrella patens
- Selaginella moellendorffii
- Oryza sativa subsp. indica
- Oryza sativa subsp. japonica
- Zea mays
- Arabidopsis lyrata
- Arabidopsis thaliana
- Carica papaya
- Populus trichocarpa
- Vitis vinifera
There are 55 gene models in this family
General references
Bienz, M. 2006. The PHD finger, a nuclear protein-interaction domain. Trends Biochem. Sci. 31(1):35-40 PUBMEDID:16297627Design qRT-PCR primers using Quantprime