Plant Transcription factor database - Universität Potsdam
version: 3.0

Arabidopsis thaliana SET Family

Description

Marmorstein. 2003: The methylation of lysine residues on histone tails is catalyzed by proteins containing a conserved SET domain. A recent flurry of structures of SET domain proteins has revealed a new protein fold and a scaffold for understanding catalysis and substrate binding by these enzymes. The prospect that histone methylation might form an epigenetic code and the implicated involvement of SET domain proteins in cancer assures that structure-function studies of these enzymes will continue until their detailed mechanism of action is determined.

Members of this family
  SHOULD possess SET domain
  SHOULD NOT possess CXC PHD zf-C2H2 domains

Domain alignments

This family is also present in:

References

There are 46 gene models in this family



Gene modelDescriptionDomains
AT1G01920.1 SET domain-containing protein SET
AT1G01920.2 SET domain-containing protein SET
AT1G02580.1 MEA (MEDEA); transcription factor SET
AT1G04050.1 SUVR1 (Arabidopsis homolog of SU(VAR)3-9 1); histone-lysine N-methyltransferase/ zinc ion binding Pre-SET SET
AT1G14030.1 ribulose-1,5 bisphosphate carboxylase oxygenase large subunit N-methyltransferase, putative Rubis-subs-bind SET
AT1G17770.1 SUVH7 (SU(VAR)3-9 HOMOLOG 7); histone-lysine N-methyltransferase/ zinc ion binding AT_hook Pre-SET SET YDG_SRA
AT1G24610.1 SET domain-containing protein Rubis-subs-bind SET
AT1G73100.1 SUVH3 (SU(VAR)3-9 HOMOLOG 3) Pre-SET SET YDG_SRA
AT1G76710.1 ASHH1/SDG26 (ASH1-RELATED PROTEIN 1) SET
AT1G76710.2 ASHH1/SDG26 (ASH1-RELATED PROTEIN 1) SET
AT1G77300.1 EFS (EARLY FLOWERING IN SHORT DAYS) SET zf-CW
AT1G77300.2 EFS (EARLY FLOWERING IN SHORT DAYS) SET zf-CW
AT2G05900.1 SET domain-containing protein / YDG/SRA domain-containing protein Pre-SET SET YDG_SRA
AT2G18850.1 similar to SET domain-containing protein [Arabidopsis thaliana] (TAIR:AT3G07670.1); similar to unnamed protein product [Vitis vinifera] (GB:CAO43237.1); contains InterPro domain SET; (InterPro:IPR001214) SET
AT2G22740.1 SUVH6 (SU(VAR)3-9 HOMOLOG 6) Pre-SET SET YDG_SRA
AT2G22740.2 SUVH6 (SU(VAR)3-9 HOMOLOG 6) Pre-SET SET YDG_SRA
AT2G23380.1 CLF (CURLY LEAF); transcription factor SET
AT2G24740.1 SDG21 (SET DOMAIN GROUP 21) AT_hook Pre-SET SET YDG_SRA
AT2G33290.1 SUVH2 (SU(VAR)3-9 HOMOLOG 2) Pre-SET SET YDG_SRA
AT2G35160.1 SUVH5 (SU(VAR)3-9 HOMOLOG 5) Pre-SET SET YDG_SRA
AT2G44150.1 ASHH3 (HISTONE-LYSINE N-METHYLTRANSFERASE ASHH3) SET
AT3G03750.1 SET domain-containing protein Pre-SET SET
AT3G03750.2 SET domain-containing protein Pre-SET SET
AT3G04380.1 SUVR4; histone-lysine N-methyltransferase Pre-SET SET
AT3G04380.2 SUVR4 Pre-SET SET
AT3G07670.1 SET domain-containing protein Rubis-subs-bind SET
AT3G55080.1 SET domain-containing protein SET
AT3G56570.1 SET domain-containing protein SET
AT3G59960.1 ASHH4 (HISTONE-LYSINE N-METHYLTRANSFERASE ASHH4) SET
AT4G02020.1 EZA1 (SWINGER); transcription factor SET
AT4G13460.1 SUVH9 (SU(VAR)3-9 HOMOLOG 9); histone-lysine N-methyltransferase/ zinc ion binding Pre-SET SET YDG_SRA
AT4G13460.2 SUVH9 (SU(VAR)3-9 HOMOLOG 9); histone-lysine N-methyltransferase/ zinc ion binding Pre-SET SET YDG_SRA
AT4G15180.1 SET domain-containing protein SET
AT4G30860.1 ASHR3 (ASH1-RELATED 3); protein binding / zinc ion binding SET
AT5G04940.1 SUVH1 (SU(VAR)3-9 HOMOLOG 1) Pre-SET SET YDG_SRA
AT5G04940.2 SUVH1 (SU(VAR)3-9 HOMOLOG 1) Pre-SET SET YDG_SRA
AT5G13960.1 SUVH4 (SU(VAR)3-9 HOMOLOG 4) Pre-SET SET YDG_SRA
AT5G14260.1 SET domain-containing protein Rubis-subs-bind SET
AT5G14260.2 SET domain-containing protein Rubis-subs-bind SET
AT5G14260.3 SET domain-containing protein Rubis-subs-bind SET
AT5G17240.1 SDG40 (SET DOMAIN GROUP 40) SET
AT5G42400.1 SET domain-containing protein (TXR7) SET
AT5G43990.1 SUVR2; histone-lysine N-methyltransferase/ zinc ion binding Pre-SET SET
AT5G43990.2 SUVR2; histone-lysine N-methyltransferase/ zinc ion binding Pre-SET SET
AT5G43990.3 SUVR2; histone-lysine N-methyltransferase/ zinc ion binding Pre-SET SET
AT5G43990.4 SUVR2; histone-lysine N-methyltransferase/ zinc ion binding Pre-SET SET

General references

Marmorstein, R. 2003. Structure of SET domain proteins: a new twist on histone methylation. Trends Biochem. Sci. 28(2):59-62 PUBMEDID:12575990