Plant Transcription factor database - Universität Potsdam
version: 3.0

Chlorella sp. NC64A SET Family


Marmorstein. 2003: The methylation of lysine residues on histone tails is catalyzed by proteins containing a conserved SET domain. A recent flurry of structures of SET domain proteins has revealed a new protein fold and a scaffold for understanding catalysis and substrate binding by these enzymes. The prospect that histone methylation might form an epigenetic code and the implicated involvement of SET domain proteins in cancer assures that structure-function studies of these enzymes will continue until their detailed mechanism of action is determined.

Members of this family
  SHOULD possess SET domain
  SHOULD NOT possess CXC PHD zf-C2H2 domains

Domain alignments

This family is also present in:


There are 14 gene models in this family

Gene modelDescriptionDomains
134525 IGS.gm_11_00371 SET
137077 IGS.gm_18_00183 SET
137958 IGS.gm_2_00425 SET
139898 IGS.gm_27_00076 SET
142047 IGS.gm_4_00188 SET
142107 IGS.gm_4_00248 SET YDG_SRA
142491 IGS.gm_40_00017 SET
142939 IGS.gm_5_00268 SET
14389 gw1.18.275.1 SET
18588 e_gw1.1.275.1 SET
24455 e_gw1.13.171.1 SET
25365 e_gw1.15.186.1 SET
35816 estExt_Genewise1Plus.C_120401 SET
58236 estExt_fgenesh3_pg.C_140039 SET YDG_SRA

General references

Marmorstein, R. 2003. Structure of SET domain proteins: a new twist on histone methylation. Trends Biochem. Sci. 28(2):59-62 PUBMEDID:12575990