Plant Transcription factor database - Universität Potsdam
version: 3.0

Carica papaya SET Family


Marmorstein. 2003: The methylation of lysine residues on histone tails is catalyzed by proteins containing a conserved SET domain. A recent flurry of structures of SET domain proteins has revealed a new protein fold and a scaffold for understanding catalysis and substrate binding by these enzymes. The prospect that histone methylation might form an epigenetic code and the implicated involvement of SET domain proteins in cancer assures that structure-function studies of these enzymes will continue until their detailed mechanism of action is determined.

Members of this family
  SHOULD possess SET domain
  SHOULD NOT possess CXC PHD zf-C2H2 domains

Domain alignments

This family is also present in:


There are 20 gene models in this family

Gene modelDescriptionDomains
evm.TU.supercontig_1.287 SET
evm.TU.supercontig_130.11 Rubis-subs-bind SET
evm.TU.supercontig_136.37 Rubis-subs-bind SET
evm.TU.supercontig_15.86 Pre-SET SET
evm.TU.supercontig_161.23 Pre-SET SET
evm.TU.supercontig_178.39 SET
evm.TU.supercontig_18.45 SET
evm.TU.supercontig_187.21 SET
evm.TU.supercontig_2.194 Rubis-subs-bind SET
evm.TU.supercontig_26.317 SET zf-CW
evm.TU.supercontig_33.185 Pre-SET SET YDG_SRA
evm.TU.supercontig_36.84 SET
evm.TU.supercontig_49.86 SET
evm.TU.supercontig_51.1 Pre-SET SET
evm.TU.supercontig_55.122 SET
evm.TU.supercontig_70.69 Pre-SET SET
evm.TU.supercontig_8.248 SET
evm.TU.supercontig_87.14 Pre-SET SET
evm.TU.supercontig_9.229 SET
evm.TU.supercontig_991.1 Rubis-subs-bind SET

General references

Marmorstein, R. 2003. Structure of SET domain proteins: a new twist on histone methylation. Trends Biochem. Sci. 28(2):59-62 PUBMEDID:12575990