Plant Transcription factor database - Universität Potsdam
version: 3.0

Coccomyxa sp. C-169 SET Family


Marmorstein. 2003: The methylation of lysine residues on histone tails is catalyzed by proteins containing a conserved SET domain. A recent flurry of structures of SET domain proteins has revealed a new protein fold and a scaffold for understanding catalysis and substrate binding by these enzymes. The prospect that histone methylation might form an epigenetic code and the implicated involvement of SET domain proteins in cancer assures that structure-function studies of these enzymes will continue until their detailed mechanism of action is determined.

Members of this family
  SHOULD possess SET domain
  SHOULD NOT possess CXC PHD zf-C2H2 domains

Domain alignments

This family is also present in:


There are 17 gene models in this family

Gene modelDescriptionDomains
16061 gw1.8.116.1 SET
16239 gw1.18.90.1 Rubis-subs-bind SET
28526 e_gw1.6.298.1 SET
28546 e_gw1.6.281.1 SET
32876 e_gw1.18.230.1 SET
34476 e_gw1.25.121.1 SET
57375 GG.C169_S01_00446 SET
59484 GG.C169_S04_00413 SET YDG_SRA
66096 GG.C169_S26_00053 SET
71231 fgeneshCV_pg.C_scaffold_2000368 AT_hook SET
71445 fgeneshCV_pg.C_scaffold_2000582 SET
71504 fgeneshCV_pg.C_scaffold_3000045 SET
74698 fgeneshCV_pg.C_scaffold_11000218 SET YDG_SRA
75348 fgeneshCV_pg.C_scaffold_14000003 Mov34 SET
79033 estExt_fgeneshCV_kg.C_90091 SET
83958 estExt_fgeneshCV_pg.C_160025 Rubis-subs-bind SET
84193 estExt_fgeneshCV_pg.C_180118 SET

General references

Marmorstein, R. 2003. Structure of SET domain proteins: a new twist on histone methylation. Trends Biochem. Sci. 28(2):59-62 PUBMEDID:12575990